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Interference of Antinuclear Antibody (ANA) in Indirect Immunofluorescence Assay (IIFA)-Based Perinuclear Antineutrophil Cytoplasmic Antibody (pANCA) Interpretation
CONCLUSIONS: ANA-positive results may interfere with the interpretation of pANCA as observed in ANA-IIFA and ENA-blot positive samples. ANA-IIFA patterns like nuclear homogenous may strongly associate this pANCA interpretation. This can help laboratories perform ANCA testing more effectively, ruling out ANA interference in ANCA screening.PMID:36338545 | PMC:PMC9629954 | DOI:10.1155/2022/1343805 (Source: Autoimmune Diseases)
Source: Autoimmune Diseases - November 7, 2022 Category: Allergy & Immunology Authors: Sangeeta Deka Deepjyoti Kalita Udaykumar Sasi Rekha Putul Mahanta Diksha Rani Ravi Shankar Anusha Krishna Raj Mithilesh Kumar Jha Gaurav Badoni Manisha Paul Shailesh Kumar Gupta Shailender Negi Anshu Singh Kuhu Chatterjee Source Type: research