Artificial DNA: PNA and XNA This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Purification and assembly of thermostable Cy5 labeled γ-PNAs into a 3D DNA nanocage
Artif DNA PNA XNA. 2014 Dec 15;5(3):e992181. doi: 10.4161/1949095X.2014.992181.ABSTRACTPNA is hybrid molecule ideally suited for bridging the functional landscape of polypeptides with the structural diversity that can be engineered with DNA nanostructures. However, PNA can be more challenging to work with in aqueous solvents due to its hydrophobic nature. A solution phase method using strain promoted, copper free click chemistry was developed to conjugate the fluorescent dye Cy5 to 2 bifunctional PNA strands as a first step toward building cyclic PNA-polypeptides that can be arranged within 3D DNA nanoscaffolds. A 3D DNA n...
Source: Artificial DNA: PNA and XNA - July 20, 2016 Category: Genetics & Stem Cells Authors: Justin D Flory Trey Johnson Chad D Simmons Su Lin Giovanna Ghirlanda Petra Fromme Source Type: research