Myelomeningocele: Long-Term Neurosurgical Management
Adv Tech Stand Neurosurg. 2024;49:95-122. doi: 10.1007/978-3-031-42398-7_6.ABSTRACTOpen spina bifida, also known as myelomeningocele (MMC), is the most challenging and severe birth defect of the central nervous system compatible with life and it is due to a failure in the dorsal fusion of the nascent neural tube during embryonic development. MMC is often accompanied by a constellation of collateral conditions, including hydrocephalus, Arnold - Chiari II malformation, brainstem disfunction, hydrosyringomyelia, tethered cord syndrome and scoliosis. Beyond early surgical repair of the dorsal defect, MMC requires lifelong care...
Source: Advances and Technical Standards in Neurosurgery - May 3, 2024 Category: Neurosurgery Authors: E Marcati G Meccariello L Mastino M Picano P D Giorgi G Talamonti Source Type: research

The Anterior Interhemispheric Transcallosal Approach to the Ventricles: How We Do It
Adv Tech Stand Neurosurg. 2024;49:123-138. doi: 10.1007/978-3-031-42398-7_7.ABSTRACTIntraventricular tumors of the lateral and third ventricles are relatively rare, accounting for 1-2% of all primary brain tumors in most large series [1-4]. They can be uniquely challenging to approach due to their deep location, propensity to become large before they are discovered, and association with hydrocephalus [5, 6]. The surgeon's goal is to develop a route to these deep lesions that will cause the least morbidity, provide adequate working space, and achieve a complete resection. This must be performed with minimal manipulation of ...
Source: Advances and Technical Standards in Neurosurgery - May 3, 2024 Category: Neurosurgery Authors: Lydia J Bernhardt Alan R Cohen Source Type: research

Treatment of Brain Arteriovenous Malformations
Adv Tech Stand Neurosurg. 2024;49:139-179. doi: 10.1007/978-3-031-42398-7_8.ABSTRACTBrain arteriovenous malformations (AVMs) are a rare entity of vascular anomalies, characteristic of anatomical shunting where arterial blood directly flows into the venous circulation. The main aim of the active treatment policy of brain AVMs is the prevention of haemorrhage. There are well-established treatment strategies that continually improve in their safety and efficacy, primarily due to the advances in imaging modalities, targeted and novel techniques, the development of alternative treatment approaches, and even better experience wi...
Source: Advances and Technical Standards in Neurosurgery - May 3, 2024 Category: Neurosurgery Authors: Vladim ír Beneš Ad éla Bubeníková Petr Skalick ý Ond řej Bradáč Source Type: research

The Father of Wisdom: "The Influence of Surgical Experience on Overall Survival in Patients with Malignant Gliomas"
CONCLUSION: Surgical treatment represents a critical step in the multimodal treatment of malignant gliomas. According to our results, surgical experience improves not only overall survival in a manner equivalent to adjuvant chemotherapy but also the quality of life. As such, a special qualification in neurooncology may prove necessary in offering these patients a second chance at life.PMID:38700685 | DOI:10.1007/978-3-031-42398-7_9 (Source: Advances and Technical Standards in Neurosurgery)
Source: Advances and Technical Standards in Neurosurgery - May 3, 2024 Category: Neurosurgery Authors: Ioan Stefan Florian Lehel Beni Zorinela Andrasoni Cristina Aldea Ioan Alexandru Florian Source Type: research

Jugular Foramen Paragangliomas
Adv Tech Stand Neurosurg. 2024;49:201-229. doi: 10.1007/978-3-031-42398-7_10.ABSTRACTParagangliomas are the most common tumors at jugular foramen and pose a great surgical challenge. Careful clinical history and physical examination must be performed to adequately evaluate neurological deficits and its chronologic evolution, also to delineate an overview of the patient performance status. Complete imaging evaluation including MRI and CT scans should be performed, and angiography is a must to depict tumor blood supply and sigmoid sinus/internal jugular vein patency. Screening for multifocal paragangliomas is advisable, with...
Source: Advances and Technical Standards in Neurosurgery - May 3, 2024 Category: Neurosurgery Authors: Guilherme H W Ceccato Luis A B Borba Source Type: research

Contemporary Management of Pediatric Brainstem Tumors
Adv Tech Stand Neurosurg. 2024;49:231-254. doi: 10.1007/978-3-031-42398-7_11.ABSTRACTBrain tumors are the second most common malignancy in childhood. Around 15-20% of pediatric brain tumors occur in the brainstem. The most common type of brainstem tumor are diffuse tumors in the ventral pons, whereas focal tumors tend to arise from the midbrain, medulla, and dorsal pons. Glioma is the most common pathological entity. Contemporary management consists of surgery, radiotherapy, chemotherapy, and other adjuvant treatment. Surgical options range from biopsy to radical excision. Biopsy can be performed for diagnostic and prognos...
Source: Advances and Technical Standards in Neurosurgery - May 3, 2024 Category: Neurosurgery Authors: Sheng-Che Chou Yu-Ning Chen Hsin-Yi Huang Meng-Fai Kuo Tai-Tong Wong Sung-Hsin Kuo Shih-Hung Yang Source Type: research

Surgery for Central Nervous System Tuberculosis in Children
Adv Tech Stand Neurosurg. 2024;49:255-289. doi: 10.1007/978-3-031-42398-7_12.ABSTRACTTuberculosis (TB) is the second most common cause of death due to a single infectious agent worldwide after COVID-19. Central nervous system tuberculosis is widely prevalent in the world, especially in the developing countries and continues to be a socioeconomic problem. It is highly devastating form of tuberculosis leading to unacceptable levels of morbidity and mortality despite appropriate antitubercular therapy. The clinical symptoms are varied and nonspecific. They can be easily overlooked. Tuberculous meningitis is the most common pr...
Source: Advances and Technical Standards in Neurosurgery - May 3, 2024 Category: Neurosurgery Authors: Dattatraya Muzumdar Puru Bansal Survender Rai Kushal Bhatia Source Type: research

Novel Surgical Approaches in Childhood Epilepsy: Laser, Brain Stimulation, and Focused Ultrasound
Adv Tech Stand Neurosurg. 2024;49:291-306. doi: 10.1007/978-3-031-42398-7_13.ABSTRACTPediatric epilepsy has a worldwide prevalence of approximately 1% (Berg et al., Handb Clin Neurol 111:391-398, 2013) and is associated with not only lower quality of life but also long-term deficits in executive function, significant psychosocial stressors, poor cognitive outcomes, and developmental delays (Schraegle and Titus, Epilepsy Behav 62:20-26, 2016; Puka and Smith, Epilepsia 56:873-881, 2015). With approximately one-third of patients resistant to medical control, surgical intervention can offer a cure or palliation to decrease the...
Source: Advances and Technical Standards in Neurosurgery - May 3, 2024 Category: Neurosurgery Authors: Kalman A Katlowitz Daniel J Curry Howard L Weiner Source Type: research

Cranial Repair in Children: Techniques, Materials, and Peculiar Issues
Adv Tech Stand Neurosurg. 2024;49:307-326. doi: 10.1007/978-3-031-42398-7_14.ABSTRACTCranial repair in children deserves particular attention since many issues are still controversial. Furthermore, literature data offer a confused picture of outcome of cranioplasty, in terms of results and complication rates, with studies showing inadequate follow-up and including populations that are not homogeneous by age of the patients, etiology, and size of the bone defect.Indeed, age has merged in the last years as a risk factor for resorption of autologous bone flap that is still the most frequent complication in cranial repair afte...
Source: Advances and Technical Standards in Neurosurgery - May 3, 2024 Category: Neurosurgery Authors: Paolo Frassanito Thomas Beez Source Type: research

Molecular Biomarkers Affecting Moyamoya Disease
Adv Tech Stand Neurosurg. 2024;49:1-18. doi: 10.1007/978-3-031-42398-7_1.ABSTRACTAlthough the pathogenetic pathway of moyamoya disease (MMD) remains unknown, studies have indicated that variations in the RING finger protein RNF 213 is the strongest susceptible gene of MMD. In addition to the polymorphism of this gene, many circulating angiogenetic factors such as growth factors, vascular progenitor cells, inflammatory and immune mediators, angiogenesis related cytokines, as well as circulating proteins promoting intimal hyperplasia, excessive collateral formation, smooth muscle migration and atypical migration may also pla...
Source: Advances and Technical Standards in Neurosurgery - May 3, 2024 Category: Neurosurgery Authors: Yong-Kwang Tu Yao-Ching Fang Source Type: research

Current Applications of VR/AR (Virtual Reality/Augmented Reality) in Pediatric Neurosurgery
Adv Tech Stand Neurosurg. 2024;49:19-34. doi: 10.1007/978-3-031-42398-7_2.ABSTRACTNeurosurgical procedures are some of the most complex procedures in medicine and since the advent of the field, planning, performing, and learning them has challenged the neurosurgeon. Virtual reality (VR) and augmented reality (AR) are making these challenges more manageable. VR refers to a virtual digital environment that can be experienced usually through use of stereoscopic glasses and controllers. AR, on the other hand, fuses the natural environment with virtual images, such as superimposing a preoperative MRI image on to the surgical fi...
Source: Advances and Technical Standards in Neurosurgery - May 3, 2024 Category: Neurosurgery Authors: Nirali Patel Katherine Hofmann Robert F Keating Source Type: research

Diagnosis and Management of Tethered Cord Syndrome
Adv Tech Stand Neurosurg. 2024;49:35-50. doi: 10.1007/978-3-031-42398-7_3.ABSTRACTTethered cord syndrome is a condition in which the spinal cord is tethered by pathological structures such as a tight filum terminale, intradural lipomas with or without a connecting extradural component, intradural fibrous adhesions, diastematomyelia, and neural placode adhesions following closure of a myelomeningocele.It usually occurs in childhood and adolescence as the spine grows in length, but it can also develop in adulthood. Symptoms of tethered cord syndrome are slowly progressive and varied. Incorrect diagnosis and inappropriate tre...
Source: Advances and Technical Standards in Neurosurgery - May 3, 2024 Category: Neurosurgery Authors: Takeshi Hara Yukoh Ohara Akihide Kondo Source Type: research

Management of Low and High Grades Spondylolisthesis
Adv Tech Stand Neurosurg. 2024;49:51-72. doi: 10.1007/978-3-031-42398-7_4.ABSTRACTSpondylolisthesis is defined as the displacement or misalignment of the vertebral bodies one on top of the other. It comes from the Greek spondlylos, which means vertebra, and olisthesis, which means sliding on a slope. The nomenclature used to refer to spondylolisthesis consists of the following elements: vertebral segment (vertebrae involved), degree of sliding of one vertebral body over the other, the position of the upper vertebral body with respect to the lower one (anterolisthesis/retrolisthesis), and finally the etiology [1].PMID:38700...
Source: Advances and Technical Standards in Neurosurgery - May 3, 2024 Category: Neurosurgery Authors: Jesus Lafuente Juan Diego Patino Lucas Capo Source Type: research

Enhanced Recovery After Surgery (ERAS) Spine Pathways and the Role of Perioperative Checklists
Adv Tech Stand Neurosurg. 2024;49:73-94. doi: 10.1007/978-3-031-42398-7_5.ABSTRACTEnhanced recovery after surgery (ERAS) proposes a multimodal, evidence-based approach to perioperative care. ERAS pathways have been shown to help reduce complications, hospital length of stay (LOS), 30-day readmission rates, pain scores, and ultimately surgical costs, while improving patient satisfaction scores and outcomes in multiple surgical subspecialties [1-6]. Numerous specialties have implemented ERAS programs across the globe, providing a foundation for spine surgeons to begin the process themselves. Over the last few years, a signif...
Source: Advances and Technical Standards in Neurosurgery - May 3, 2024 Category: Neurosurgery Authors: Scott C Robertson Source Type: research

Myelomeningocele: Long-Term Neurosurgical Management
Adv Tech Stand Neurosurg. 2024;49:95-122. doi: 10.1007/978-3-031-42398-7_6.ABSTRACTOpen spina bifida, also known as myelomeningocele (MMC), is the most challenging and severe birth defect of the central nervous system compatible with life and it is due to a failure in the dorsal fusion of the nascent neural tube during embryonic development. MMC is often accompanied by a constellation of collateral conditions, including hydrocephalus, Arnold - Chiari II malformation, brainstem disfunction, hydrosyringomyelia, tethered cord syndrome and scoliosis. Beyond early surgical repair of the dorsal defect, MMC requires lifelong care...
Source: Advances and Technical Standards in Neurosurgery - May 3, 2024 Category: Neurosurgery Authors: E Marcati G Meccariello L Mastino M Picano P D Giorgi G Talamonti Source Type: research