NHS Evidence expert commentary: Citalopram for the treatment of depression
Source: NHS Evidence
Area: News
The February edition of 'Eyes on Evidence', the free monthly e-bulletin from NHS Evidence covering major new published evidence as it emerges with an explanation about what it means for current practice, includes an expert commentary on new data from a Cochrane review of 37 RCTs which assessed the efficacy, acceptability and tolerability of citalopram compared with other antidepressants in the acute-phase treatment of major depression in over 6000 patients.
Citalopram did not differ from most antidepressants in the primary outcome, the number of patients who responded to treatmen...
Source: NeLM - Mental Health - February 14, 2013 Category: Psychiatry Source Type: news
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Source: PRWeb: Medical Pharmaceuticals - January 27, 2013 Category: Pharmaceuticals Source Type: news
If antidepressant-induced hyponatraemia has been diagnosed, how should the depression be treated?
Source: East Anglia Medicines Information Service
Area: Evidence > Medicines Q & A
If the hyponatraemia is mild (125-134mmol/litre serum sodium) and there is no other cause for the hyponatraemia, discontinue the antidepressant and monitor serum sodium levels daily until they are within normal range or if asymptomatic, consider fluid restriction.
If the patient has serum sodium below 125mmol/litre, discontinue the antidepressant immediately and treat medically for hyponatraemia.
After serum sodium levels have normalised, choose another appropriate antidepressant.
If the patient developed hyponatraemia whilst on...
Source: NeLM - Mental Health - January 2, 2013 Category: Psychiatry Source Type: news
