The Role of Skin Substitutes in Acute Burn and Reconstructive Burn Surgery: An Updated Comprehensive Review

Semin Plast Surg DOI: 10.1055/s-0042-1743455Burns disrupt the protective skin barrier with consequent loss of cutaneous temperature regulation, infection prevention, evaporative losses, and other vital functions. Chronically, burns lead to scarring, contractures, pain, and impaired psychosocial well-being. Several skin substitutes are available and replace the skin and partially restore functional outcomes and improve cosmesis. We performed a literature review to update readers on biologic and synthetic skin substitutes to date applied in acute and reconstructive burn surgery. Improvement has been rapid in the development of skin substitutes in the last decade; however, no available skin substitute fulfills criteria as a perfect replacement for damaged skin. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text

Source: Seminars in Plastic Surgery - April 12, 2022 Category: Cosmetic Surgery Authors: Palackic, Alen Duggan, Robert P. Campbell, Matthew S. Walters, Elliot Branski, Ludwik K. Ayadi, Amina El Wolf, Steven E. Tags: Review Article Source Type: research