Oral histoplasmosis presenting as a solitary ulcer on tongue in an immunocompetent adult

Histoplasmosis or Darling's disease is caused by the opportunistic dimorphic fungi Histoplasma capsulatum, ubiquitous in soil contaminated by bird or bat excreta. Humans get infected by inhaling spores of the organism. The organism mainly affects the aerodigestive tracts of susceptible individuals but it can also involve other organs and occur in disseminated and localised forms. Most cases have been associated with immunosuppression particularly in HIV infected individuals in whom disseminated disease is more common, but immunocompetent patients with underlying risk factors may develop histoplasmosis very rarely.

Source: The American Journal of Medicine - March 13, 2022 Category: General Medicine Authors: Kaushiki Hajra, Uddalak Chakraborty, Kingshuk Chatterjee, Srinjani Mukherjee, Saswati Halder Tags: Clinical communication to the Editor Source Type: research