Inhibitory Effect of Resveratrol on LPS-induced Glomerular Mesangial Cells Proliferation and TGF- β1 Expression via Sphingosine Kinase 1 Pathway

ConclusionRSV inhibited LPS-induced GMCs proliferation and TGF- β1 expression, which may be independent of its hypoglycemic effect on preventing the development of mesangial cell fibrosis and closely related to the direct inhibition of SphK1 pathway.
Source: Chinese Journal of Integrative Medicine - Category: Internal Medicine Source Type: research