Examining the cooperativity mode of antibody and CD8 < sup > + < /sup > T cell immune responses for vaccinology

Trends Immunol. 2021 Sep 4:S1471-4906(21)00155-1. doi: 10.1016/j.it.2021.08.003. Online ahead of print.ABSTRACTA fundamental unsolved issue in vaccine design is how neutralizing antibodies and cytotoxic CD8+ T cells cooperate numerically in controlling virus infections. We hypothesize on a viewpoint for the multiplicative cooperativity between neutralizing antibodies and CD8+ T cells and propose how this might be exploited for improving vaccine-induced protective immunity.PMID:34561159 | DOI:10.1016/j.it.2021.08.003
Source: Trends in Immunology - Category: Allergy & Immunology Authors: Source Type: research