Follicular Helper-like T Cells in the Lung Highlight a Novel Role of B Cells in Sarcoidosis

CONCLUSIONS: Active T cell / B cell cooperation and local production of potentially pathogenic antibodies in the inflamed lung represents a novel pathomechanism in sarcoidosis and should be considered from both diagnostic and therapeutic perspectives.PMID:34534436 | DOI:10.1164/rccm.202012-4423OC

Source: Am J Respir Crit Car... - September 17, 2021 Category: Intensive Care Authors: Laura Bauer Lisa Jasmin M üller Sarah M Volkers Frederik Heinrich Mir-Farzin Mashreghi Clemens Ruppert Leif E Sander Andreas Hutloff Source Type: research