Caprine PRNP polymorphisms N146S and Q222K are associated with proteolytic cleavage of PrPC

Expression of the cellular prion protein (PrPC) is crucial for the development of prion diseases. Amino acid changes in PrPC or a reduced amount of PrPC may modulate disease resistance. The relative abundance of ...

Source: Genetics Selection Evolution - June 19, 2021 Category: Genetics & Stem Cells Authors: Sally A. Madsen-Bouterse, Paula Stewart, Helen Williamson, David A. Schneider and Wilfred Goldmann Tags: Short communication Source Type: research