Could Certain Diabetes Drugs Fight Asthma, Too?

Title: Could Certain Diabetes Drugs Fight Asthma, Too?Category: Health NewsCreated: 5/26/2021 12:00:00 AMLast Editorial Review: 5/26/2021 12:00:00 AM
Source: MedicineNet Asthma General - Category: Respiratory Medicine Source Type: news

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[Ghanaian Times] A fall-out on the COVID-19 pandemic is the impact on health care on persons with chronic and non-communicable diseases. Persons with hypertension, heart failure, diabetes, asthma, and cancer are regarded as the most vulnerable to COVID-19. Persons with such diseases are most likely to suffer the complications of COVID-19. The presence of these diseases makes COVID-19 worse. Infection with COVID-19 also makes these diseases worse. Yet these vulnerable persons are reluctant to go for scheduled reviews becaus
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
In this report, two cases who developed rhino-orbito-cerebral mucormycosis shortly after having COVID-19 infection were presented. The first case was a 68-year old woman who admitted to our clinic with orbital cellulitis in her left eye and had a known diagnosis of asthma and rheumatoid arthritis. She was diagnosed with COVID-19 pneumonia 40 days ago, stayed in the intensive care unit for a long time, and received pulse steroid (1000 mg methylprednisolone), interleukin-1 (IL-1) inhibitor (anakinra) and broad-spectrum antibiotic treatments together with antiviral therapy during this period. The second case was a 63-year-old...
Source: Mikrobiyoloji Bulteni - Category: Microbiology Authors: Source Type: research
Am J Physiol Lung Cell Mol Physiol. 2021 Oct 20. doi: 10.1152/ajplung.00202.2021. Online ahead of print.ABSTRACTIncreased insulin is associated with obesity-related airway hyperreactivity and asthma. We tested whether the use of metformin, an anti-diabetic drug used to reduce insulin resistance, can reduce circulating insulin, thereby preventing airway hyperreactivity in rats with dietary obesity. Male and female rats were fed a high- or low-fat diet for 5 weeks. Some male rats were simultaneously treated with metformin (100 mg/kg, p.o.). In separate experiments, after 5 weeks of a high-fat diet, some rats were switched to...
Source: Am J Physiol Lung Ce... - Category: Respiratory Medicine Authors: Source Type: research
Abstract Due to an ageing population and improvements in healthcare, the prevalence of chronic disease (CD) is rising in Ireland and internationally. In Ireland, CD care is often characterised by siloed, reactive care, culminating in repeated hospital admissions. This is neither patient-centred nor sustainable. Health services need to evolve to meet changing population need. How can Irish health services meet population need in a sustainable way? The National Clinical Programmes (NCPs) in Ireland draw together healthcare professionals from primary and secondary care to improve specific areas within the health service....
Source: The European Journal of Public Health - Category: General Medicine Source Type: research
Biomed Pharmacother. 2021 Nov;143:112175. doi: 10.1016/j.biopha.2021.112175. Epub 2021 Sep 27.ABSTRACTWithania somnifera (L.) Dunal (Solanaceae) has been used as a traditional Rasayana herb for a long time. Traditional uses of this plant indicate its ameliorative properties against a plethora of human medical conditions, viz. hypertension, stress, diabetes, asthma, cancer etc. This review presents a comprehensive summary of the geographical distribution, traditional use, phytochemistry, and pharmacological activities of W. somnifera and its active constituents. In addition, it presents a detailed account of its presence as...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: Source Type: research
This study assessed the validity of the Global Assessment of Severity of Illness (GASI), a single-item scale designed for quick and simple assessment of illness severity in children with various chronic physical conditions. Study objectives were to examine validity, reliability, and responsiveness of the GASI. Clinicians assessed the severity of asthma, food allergy, epilepsy, diabetes, and juvenile arthritis in 55 children, and parents reported on children ’s health-related quality of life. Area under the curve (AUC) computed by logistic regression and Kendall’s Tau-c (τc) assessed the strength of associat...
Source: Health Services and Outcomes Research Methodology - Category: Statistics Source Type: research
Accumulating studies have shown that microbes are closely related to human diseases. In this paper, a novel method called MSBMFHMDA was designed to predict potential microbe–disease associations by adopting multi-similarities bilinear matrix factorization. In MSBMFHMDA, a microbe multiple similarities matrix was constructed first based on the Gaussian interaction profile kernel similarity and cosine similarity for microbes. Then, we use the Gaussian interaction profile kernel similarity, cosine similarity, and symptom similarity for diseases to compose the disease multiple similarities matrix. Finally, we integrate t...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Cad Saude Publica. 2021 Oct 8;37(10):e00049821. doi: 10.1590/0102-311X00049821. eCollection 2021.ABSTRACTIn a context of community transmission and shortage of vaccines, COVID-19 vaccination should focus on directly reducing the morbidity and mortality caused by the disease. It was thus essential to define priority groups for vaccination by the Brazilian National Immunization Program (PNI in Portuguese), based on the risk of hospitalization and death from the disease. We calculated overrisk according to sex, age group, and comorbidities using hospitalization and death records from severe acute respiratory illness with conf...
Source: Cadernos de Saude Publica - Category: International Medicine & Public Health Authors: Source Type: research
ConclusionsThis study provides evidence to support the public health potential ofparkrun though targeted initiatives such as the PROVE project and provides a critical reflection on what worked and what did not work when delivering the project. The findings have relevance for organisations wishing to implement similar outreach initiatives using a volunteer workforce, including recommendations for resource management, communication, leadership, fostering volunteer autonomy and defining and capturing success.
Source: BMC Sports Science, Medicine and Rehabilitation - Category: Sports Medicine Source Type: research
Health Soc Work. 2021 Oct 8:hlab025. doi: 10.1093/hsw/hlab025. Online ahead of print.ABSTRACTThe relationship between chronic medical conditions and PTSD within-race in Black adults is not well understood and there exists a dearth of empirical research investigating the gender differences. Cross-sectional data from the National Survey of American Life were used to examine the relationship between PTSD and obesity, hypertension, diabetes, heart disease, and asthma (five of the most commonly identified COVID-19 underlying medical conditions) among Black adults in the United States. Results from modified Poisson regression an...
Source: Health and Social Work - Category: International Medicine & Public Health Authors: Source Type: research
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