Carcinosarcoma of Uterus: a Case Report

AbstractCarcinosarcoma is a malignant mixed M üllerian tumor with a highly malignant, biphasic tumor consisting of both epithelial and mesenchymal components. A 59-year-old nulligravida came with postmenopausal bleeding. Hysteroscopy revealed highly vascular polypoidal mass with prominent vasculature. Gross examination of specimen showed a pol ypoid mass, occupying whole uterine cavity and invading more than half of myometrium. Immunohistochemical analysis showed epithelial component AE1/AE3 and stromal component desi and p16. Tumor cells were negative for ER. As carcinosarcoma is a highly aggressive less common variant of endometrial can cer, early diagnosis and aggressive treatment are important to minimize morbidity and overall survival.
Source: The Journal of Obstetrics and Gynecology of India - Category: OBGYN Source Type: research