The histopathology of proliferative verrucous leukoplakia

Proliferative verrucous leukoplakia (PVL) is a chronic, aggressive oral mucosal condition with a poor long-term prognosis. It has no specific, defining microscopic characteristics and is a clinical rather than histological diagnosis. PVL may appear clinicopathologically innocuous in its early stages, but there are clues that can alert the histopathologist to a dangerous condition, such as the recognition of hyperkeratoses which, though apparently benign, are inconsistent with well-defined reactive entities.

Source: Diagnostic Histopathology - February 25, 2021 Category: Pathology Authors: A William Barrett Tags: Mini-symposium: Head and neck pathology Source Type: research