Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis

RCT (n=432) found no difference for dexmedetomidine vs propofol in the number of days alive without delirium or coma (10.7 vs. 10.8 days; OR 0.96, 95%CI 0.74-1.26), ventilator-free days (23.7 vs. 24.0 days, 0.98, 0.63-1.51) or death at 90 days (38% vs. 39%; HR 1.06, 0.74-1.52).

Source: Current Awareness Service for Health (CASH) - February 4, 2021 Category: Consumer Health News Source Type: news