The Reply

The letter by Dr Stricker regarding Radonjic's analysis of Christina's World,1 which casts the famous work of art in a new light, is certainly welcome. Rather than accepting the usual diagnosis of Charcot-Marie-Tooth (CMT) disease, Dr Stricker proposes Lyme disease as the condition that leads the woman to take such a vulnerable pose. Although such a novel interpretation is an important part of the ongoing discourse on this piece, upon deeper analysis there are several aspects to further explore.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Letter Source Type: research

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Dr. Auwaerter has consulted for DiaSorin, Adaptive Biotherapeutics and Pfizer; has done research sponsored by MicroB-Plex; has been an expert witness in malpractice cases involving Lyme disease; and is an unpaid board member of the American Lyme Disease Foundation. Dr. Kobayashi has no disclosures. Dr. Wormser reports receiving research grants from the Institute for Systems Biology and Pfizer, Inc. He has been an expert witness in malpractice cases involving Lyme disease; and is an unpaid board member of the non-profit American Lyme Disease Foundation.
Source: The American Journal of Medicine - Category: General Medicine Authors: Source Type: research
OBJECTIVE: Lyme borreliosis is a tick-borne infectious disease that may confer an increased risk of mental disorders, but previous studies have been hampered by methodological limitations, including small sample sizes. The authors used a nationwide retrosp...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Risk Factor Prevalence, Injury Occurrence Source Type: news
People in Denmark diagnosed with Lyme disease in a hospital went on to have 28% higher rates of mental disorders and were twice as likely to have attempted suicide, compared with those without the diagnosis, according to astudy published Wednesday inAJP in Advance. Having more than one episode of Lyme disease was associated with a higher rate of mental disorders, affective disorders, and suicide attempts.According to theCDC, nearly half a million people a year in the United States are treated for Lyme disease (also known as Lyme borreliosis), the most common vector-borne disease, and the areas where Lyme disease is common ...
Source: Psychiatr News - Category: Psychiatry Tags: ajp in advance CDC Denmark hospitalized infections lyme disease mental disorders suicide Source Type: research
Biomacromolecules. 2021 Jul 29. doi: 10.1021/acs.biomac.1c00714. Online ahead of print.ABSTRACTNeurodegenerative disorders are among the most common diseases in modern society. However, the molecular bases of diseases such as multiple sclerosis or Charcot-Marie-Tooth disease remain far from being fully understood. Research in this field is limited by the complex nature of native myelin and by difficulties in obtaining good in vitro model systems of myelin. Here, we introduce an easy-to-use model system of the myelin sheath that can be used to study myelin proteins in a native-like yet well-controlled environment. To this e...
Source: Biomacromolecules - Category: Biochemistry Authors: Source Type: research
CONCLUSIONS: Individuals diagnosed with Lyme borreliosis in the hospital setting had an increased risk of mental disorders, affective disorders, suicide attempts, and suicide. Although the absolute population risk is low, clinicians should be aware of potential psychiatric sequelae of this global disease.PMID:34315282 | DOI:10.1176/appi.ajp.2021.20091347
Source: The American Journal of Psychiatry - Category: Psychiatry Authors: Source Type: research
Radonjic's article about Andrew Wyeth's masterpiece, Christina's World,1 is thought-provoking even though it simply covers old ground about the possible diagnosis of Charcot-Marie-Tooth (CMT) polyneuropathy in the woman who is the subject of the painting.2 As is often the case in art and medicine, however, viewing a picture with fresh eyes may reveal new possibilities. Therefore, it is worthwhile to consider a different diagnosis in this young woman of Scandinavian descent lying in a lush New England field of grass.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Letter Source Type: research
Discussionby Dr MGK Murthy, Dr GA PrasadChronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is characterized clinically by a progressive or relapsing course of many months to years of symptoms similar to compressive myelopathy.Etiology Remains unknown, but T-cell activation in nerves plays an important role in the pathogenesis of CIDP&antigens in Schwann cells have been identified.PathologicallyCIDP is characterized by mononuclear cell infiltrates, edema, segmental demyelination, and remyelination&“onion bulb formation” which describes enlarged fascicles with increased endoneural connectiv...
Source: Sumer's Radiology Site - Category: Radiology Authors: Source Type: blogs
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