Proteasome inhibitors reduce thrombospondin-1 release in human dysferlin-deficient myotubes

Dysferlinopathies are a group of muscle disorders causing muscle weakness and absence or low levels of dysferlin, a type-II transmembrane protein and the causative gene of these dystrophies. Dysferlin is impli...

Source: BMC Musculoskeletal Disorders - November 27, 2020 Category: Orthopaedics Authors: Esther Fern ández-Simón, Cinta Lleixà, Xavier Suarez-Calvet, Jordi Diaz-Manera, Isabel Illa, Eduard Gallardo and Noemí de Luna Tags: Research article Source Type: research