Risk score for predicting primary cesarean delivery in women with gestational diabetes mellitus

Women with gestational diabetes mellitus (GDM) have a higher risk of cesarean delivery (CD) than glucose-tolerant women. The aim of this study was to develop and validate a risk score for predicting primary CD...
Source: BMC Pregnancy and Childbirth - Category: OBGYN Authors: Tags: Research article Source Type: research

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The prevalence of gestational diabetes mellitus in Australia has been rising in line with the increased incidence of maternal overweight and obesity. Women with gestational diabetes mellitus, high body mass in...
Source: BMC Pregnancy and Childbirth - Category: OBGYN Authors: Tags: Research Source Type: research
Gestational diabetes mellitus (GDM) is a high glucose level detected during pregnancy and usually it disappears after 42 days of post partum [1]. Like others diabetes mellitus, it affects the metabolism of glucose. Different report estimates the prevalence of GDM from 1% to 28% [2,3]. The prevalence of GDM was increasing at alarming rate in low and middle income countries where access to basic medical service was scarce [4].
Source: Primary Care Diabetes - Category: Primary Care Authors: Tags: Original research Source Type: research
In Sweden, about 0.5% of the population live with diabetes mellitus type 1 (DM1), and among these, approximately 500 women give birth every year [1,2]. DM1 during pregnancy and labor is associated with an increased risk of maternal and fetal complications, and pregnant women with DM1 have an increased risk of developing preeclampsia. The fetus also has a higher risk of neonatal morbidity and mortality due to congenital malformations, being large for gestational age (LGA), shoulder dystocia, cesarean sectio, preterm birth, hypoglycemia, hyper-bilirubin, and stillbirth [3].
Source: Primary Care Diabetes - Category: Primary Care Authors: Tags: Original research Source Type: research
Clin Mol Hepatol. 2021 Sep 17. doi: 10.3350/cmh.2021.0205. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Maternal and fetal outcomes in pregnant patients with NAFLD have been largely unexplored. To determine the level of evidence associated with both maternal and fetal outcomes in pregnant women with NAFLD.METHOD: We conducted a comprehensive literature search. The studies included pregnant patients with a previous, current or subsequent diagnosis of NAFLD. We used a random-effects model using odds ratios (OR) with 95% confidence intervals (CI).RESULTS: Twenty two studies, with 13641 female NAFLD patients were reviewe...
Source: Clinical and molecular hepatology - Category: Gastroenterology Authors: Source Type: research
Clin Mol Hepatol. 2021 Sep 17. doi: 10.3350/cmh.2021.0205. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Maternal and fetal outcomes in pregnant patients with NAFLD have been largely unexplored. To determine the level of evidence associated with both maternal and fetal outcomes in pregnant women with NAFLD.METHOD: We conducted a comprehensive literature search. The studies included pregnant patients with a previous, current or subsequent diagnosis of NAFLD. We used a random-effects model using odds ratios (OR) with 95% confidence intervals (CI).RESULTS: Twenty two studies, with 13641 female NAFLD patients were reviewe...
Source: Clinical and molecular hepatology - Category: Gastroenterology Authors: Source Type: research
Clin Mol Hepatol. 2021 Sep 17. doi: 10.3350/cmh.2021.0205. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Maternal and fetal outcomes in pregnant patients with NAFLD have been largely unexplored. To determine the level of evidence associated with both maternal and fetal outcomes in pregnant women with NAFLD.METHOD: We conducted a comprehensive literature search. The studies included pregnant patients with a previous, current or subsequent diagnosis of NAFLD. We used a random-effects model using odds ratios (OR) with 95% confidence intervals (CI).RESULTS: Twenty two studies, with 13641 female NAFLD patients were reviewe...
Source: Clinical and molecular hepatology - Category: Gastroenterology Authors: Source Type: research
AbstractGestational diabetes mellitus (GDM) is the most common form of dysglycaemia during pregnancy. GDM is defined as hyperglycemia diagnosed for the first time during pregnancy, most commonly during the second or third trimester. GDM can be harmful to both the mother and the offspring. Complications to fetuses include excessive birthweight and preterm birth, while women with GDM are more susceptible to gestational hypertension, pre-eclampsia, and postpartum abnormal glucose intolerance (pAGT).
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: UPDATE Source Type: research
Eur J Endocrinol. 2021 Sep 1:EJE-21-0635.R1. doi: 10.1530/EJE-21-0635. Online ahead of print.ABSTRACTAIMS: To assess whether in women with gestational diabetes mellitus (GDM), postpartum plasma glycated CD59 (pGCD59) levels predict conversion to glucose intolerance diagnosed with an oral glucose tolerance test (OGTT).METHODS: Blood levels of pGCD59 were measured in a case-control study of 105 women with GDM who underwent a 75g OGTT three months postpartum. The 35 postpartum glucose intolerant cases were individually matched for age, BMI, ethnic origin and parity with 70 women with GDM but normal postpartum OGTT (controls)....
Source: European Journal of Endocrinology - Category: Endocrinology Authors: Source Type: research
One of the most prevalent pregnancy-related complications is Gestational Diabetes Mellitus (GDM) [1]. It is defined as inadequate insulin secretory response and hyperglycemia in pregnant women without pre-existing diabetes [1]. The prevalence of GDM varies across countries. In high-income countries, it is reported to be between 1.7 –11.6% [2], while in East and Southeast Asia, this rate is estimated to be 10.1% (6.5%–15.7%) [3]. Age, high body mass index (BMI), strong family history of diabetes in first and second degree relatives, and previous history of gestational diabetes are among the most important risk f...
Source: Primary Care Diabetes - Category: Primary Care Authors: Tags: Review Source Type: research
CONCLUSION: Apelin-13, possibly by activating the PI3K/AKT pathway, could improve the glucose and lipid metabolism, reduce the damage caused by oxidative stress and inflammatory reaction, and protect the pancreas islet, thereby improving the pregnancy outcome of GDM mice.PMID:34521048 | DOI:10.1016/j.imbio.2021.152135
Source: Immunobiology - Category: Allergy & Immunology Authors: Source Type: research
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