Biologics

Platelet-rich plasma is an orthobiologic agent defined as a platelet concentration of at least 1,000,000 platelets/ μl in 5 ml of plasma and contains a 3 to 8 fold increase in platelet concentrations from baseline1. While intially used in oral maxillofacial and cardiac surgery throughout the 1980s and 1990s2,3, its application has been increasingly utilized in the field of orthopedics to treat a variety of joint , tendon, and ligamentous injuries. Following a blood draw of autologous blood, centrifugation is performed to separate the blood components into different layers: red blood cells precipitate to the bottom, the middle layer is composed of white blood cells and platelets4, and the remaining plasma (p latelet poor plasma) forms the top most layer.

Source: Techniques in Vascular and Interventional Radiology - October 5, 2020 Category: Radiology Authors: Robert L Bowers, Wesley D Troyer, R Amadeus Mason, Kenneth R Mautner Source Type: research