Transmitting the Signal: Structure of the β1-Adrenergic Receptor-Gs Protein Complex

In this issue of Molecular Cell, Su et  al. (2020) report a cryo-EM structure of the β1-adrenergic receptor (β1AR) in complex with a heterotrimeric Gs protein, which offers novel insights into receptor activation and provides a structural framework to better understand the transducer-coupling mechanism for adrenergic receptors.

Source: Molecular Cell - September 30, 2020 Category: Cytology Authors: Shubhi Pandey, Shirsha Saha, Arun K. Shukla Tags: Preview Source Type: research