A Complex Acetate-ment: Timing of Exposure Determines Memory T Cell Fate.

A Complex Acetate-ment: Timing of Exposure Determines Memory T Cell Fate.
Cell Metab. 2020 Sep 01;32(3):325-327
Authors: Heieis GA, Everts B
Abstract
In this issue of Cell Metabolism, Balmer et al. show that the timing and concentration of acetate exposure is critical to how it is metabolized by and affects the function of CD8 T cells. When abundantly present at the time of reactivation, acetate rewires CD8 T cell metabolism to suppress their reactivation and limit inflammation.
PMID: 32877687 [PubMed - as supplied by publisher]

Source: Cell Metabolism - August 31, 2020 Category: Cytology Authors: Heieis GA, Everts B Tags: Cell Metab Source Type: research