Dearomatization of a 3-Hydroxypyridine Through an Unexpected Oxidative Deformylation Process: An Entry to Azacyclohexadienones
Synlett DOI: 10.1055/s-0040-1706870 Phenols are well-known precursors of cyclohexadienones, which have widespread applications in organic synthesis. In contrast, their hydroxypyridine counterparts have not been explored yet. An unprecedented oxidative dearomatization of a 3-hydroxypyridine involving an unexpected deformylation step is reported. The chemical reactivity of the resulting unreported azacyclohexadiene-type compound was also explored. [...] © Georg Thieme Verlag Stuttgart · New YorkArticle in Thieme eJournals: Table of contents | Abstract | Full text
Source: Synlett - Category: Chemistry Authors: Mabrouki, Afef Le Nahenec-Martel, Patricia Kriaa, Abdelkader Hedhli, Ahmed Renard, Pierre-Yves Sabot, Cyrille Tags: letter Source Type: research