Androgen excess and diagnostic steroid biomarkers for nonclassic 21-hydroxylase deficiency without cosyntropin stimulation.

Conclusions: Adrenal 11-oxyandrogens are disproportionately elevated compared to conventional androgens in N21OHD. Steroid panels can accurately diagnose N21OHD in unstimulated blood tests.
PMID: 32487778 [PubMed - in process]

Source: European Journal of Endocrinology - June 5, 2020 Category: Endocrinology Authors: Turcu AF, El-Maouche D, Zhao L, Nanba AT, Gaynor A, Veeraraghavan P, Auchus RJ, Merke DP Tags: Eur J Endocrinol Source Type: research