Oral angioleiomyoma: a case report and considerations on differential diagnosis

We report a case of an angioleiomyoma occurring in the maxillary gingiva. The lesion was painless, with a lobulated surface, fibrous in consistency, and firm upon palpation. Microscopic examination showed an encapsulated tumor mass composed of large vascular channels of varying calibers, surrounded by thick walls of irregularly arranged, spindle-shaped cells, which were immunopositive for smooth-muscle actin. It is sometimes difficult to differentiate an angioleiomyoma from other spindle-cell tumors, thus we emphasize its histological differential diagnosis.Angioleiomiomas são tumores mesenquimais benignos derivados de músculo liso que raramente ocorrem na cavidade oral. Relatamos um caso de angioleiomioma na gengiva maxilar. A lesão era indolor, com superfície lobulada, consistência fibrosa e firme à palpação. O exame histológico mostrou massa tumoral encapsulada, composta por grandes canais vasculares de diferentes calibres, circundados por paredes espessas de células fusiformes dispostas de forma irregular, as quais se apresentavam imunopositivas para actina de músculo liso. A distinção entre angioleiomioma e outros tumores de células fusiformes algumas vezes é difícil e, por essa razão, enfatizamos seu diagnóstico diferencial histológico.

Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - January 11, 2014 Category: Pathology Source Type: research