Necrolytic acral erythema.

Necrolytic acral erythema.
Dermatol Online J. 2013;19(12):20709
Authors: Yost JM, Boyd KP, Patel RR, Ramachandran S, Franks AG
Abstract
Necrolytic acral erythema is a rare, cutaneous manifestation of hepatitis C virus infection that is characterized by erythematous, violaceous or dusky papules, blisters, and/or erosions in the early stages and by well-demarcated, hyperkeratotic, targetoid plaques with a peripheral rim of macular erythema, secondary lichenification and hyperpigmentation, and overlying fine micaceous or necrotic-appearing scale in the later stages. Because most topical modalities prove ineffective, treatment of the underlying viral infection or therapeutic zinc supplementation are required for clinical improvement.
PMID: 24365000 [PubMed - in process]

Source: Dermatol Online J - December 27, 2013 Category: Dermatology Authors: Yost JM, Boyd KP, Patel RR, Ramachandran S, Franks AG Tags: Dermatol Online J Source Type: research