NICE publishes rapid guidance on managing COVID-19 in primary care

New guidance on symptom management in patients with suspected and confirmed COVID-19 in the community, along with specific advice on managing those with pneumonia, have been published by NICE.
Source: GP Online News - Category: Primary Care Tags: Coronavirus Source Type: news

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COVID-19 presents varied clinical features, ranging from asymptomatic to ARDS. The most common symptoms at onset of COVID-19 include fever, cough, and shortness of breath. 2 External 0 0 0 1 false true false%> Yet about 80% of infections are mild (no pneumonia manifestations) or asymptomatic, though still contagious. 2 External 0 0 0 2 false true false%> If the virus is not causing serious symptoms, people are less likely to r...
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
This article provides a Bayesian methodology to estimate outbreak size from one or more surveillance systems such as virologic testing of pneumonia cases or samples from a network of general practitioners.
Source: Epidemiology - Category: Epidemiology Tags: Infectious diseases Source Type: research
Vidya M Mahalmani, Dhruv Mahendru, Ankita Semwal, Sukhmeet Kaur, Harpinder Kaur, Phulen Sarma, Ajay Prakash, Bikash MedhiIndian Journal of Pharmacology 2020 52(2):117-129 In December 2019, severe acute respiratory syndrome-coronavirus-2, a novel coronavirus, initiated an outbreak of pneumonia from Wuhan in China, which rapidly spread worldwide. The clinical characteristics of the disease range from asymptomatic cases or mild symptoms, which include nonspecific symptoms such as fever, cough, sore throat, headache, and nasal congestion to severe cases such as pneumonia, respiratory failure demanding mechanical ventilation t...
Source: Indian Journal of Pharmacology - Category: Drugs & Pharmacology Authors: Source Type: research
The coronavirus disease 2019 (COVID-19) pandemic poses the most significant modern-day public health challenge since the Spanish flu of 1918, causing substantial morbidity and mortality worldwide.1 Coronavirus disease 2019 predominantly affects the respiratory system, causing severe pneumonia and respiratory distress syndrome. There is also involvement of multiple organs, and the cardiovascular system has been implicated. In a recent study to investigate characteristics and prognostic factors in 339 elderly patients with COVID-19, Wang and colleagues observed a high proportion of severe and critical cases as well as high fatality rates.
Source: Journal of Infection - Category: Infectious Diseases Authors: Tags: Letter to the Editor Source Type: research
Conclusions Although clinical data supporting an influence of all these drugs on the course of the disease are limited, this is an interesting background for further research that might help unravel the complex mechanisms underlying the link between COVID-19 and diabetes.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research
DiscussionWhile awaiting a vaccine, hygiene measures, social distancing and personal protective equipment are the only primary prophylaxis measures against SARS-CoV-2, but they have not been sufficient to protect our healthcare professionals. Some evidence of thein vitro efficacy of hydroxychloroquine against this virus is known, along with some clinical data that would support the study of this drug in the chemoprophylaxis of infection. However, there are still no data from controlled clinical trials in this regard. If our hypothesis is confirmed, hydroxychloroquine can help professionals fight this infection with more gu...
Source: Trials - Category: Research Source Type: clinical trials
In December 2019, reports of viral pneumonia came out of Wuhan city in Hubei province in China. In early 2020, the causative agent was identified as a novel coronavirus (CoV) sharing some sequence similarity with SARS-CoV that caused the severe acute respiratory syndrome outbreak in 2002. The new virus, named SARS-CoV-2, is highly contagious and spread rapidly across the globe causing a pandemic of what became known as coronavirus infectious disease 2019 (COVID-19). Early observations indicated that cardiovascular disease (CVD) patients are at higher risk of progression to severe respiratory manifestations of COVID-19 incl...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
(CNN) — A five-day course of the antiviral drug remdesivir sped recovery in moderately ill patients with pneumonia from Covid-19, drugmaker Gilead Sciences announced in a statement Monday. It’s more evidence that the drug can help patients, however outside experts are not calling this a “game changer” quite yet. Coronavirus patients who were hospitalized, but not sick enough to need oxygen from a ventilator, were more likely to recover after a five-day course of remdesivir than those given the current standard of care alone, Gilead said. The results from the Phase III clinical trial on the drug have...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health CNN Coronavirus remdesivir Source Type: news
Remdesivir can help patients with moderate Covid-19 pneumonia recover, drugmaker Gilead Sciences announced Monday. Outside experts are not calling this a "game changer" quite yet.
Source: - Health - Category: Consumer Health News Source Type: news
Resumo Os sintomas respirat órios, principalmente o desenvolvimento de quadros de síndrome do desconforto respiratório agudo grave, dominam a discussão e as preocupações iniciais da população e dos profissionais de saúde. Entretanto, o sistema cardiovascular é bastante afetado por essas condições e, muitas vezes, é o responsável por complicações e mortalidade desses pacientes. Com o objetivo de mostrar as implicações cardiovasculares em pacientes infectados pela COVID-19 e a importância do iso...
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
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