Mammillary Fistula as a Possible Manifestation of Hidradenitis Suppurativa
Publication date: Available online 29 March 2020Source: Actas Dermo-Sifiliográficas (English Edition)Author(s): M.J. Sánchez-Pujol, P. Álvarez-Chinchilla, A. Docampo-Simón, J.C. Pascual Ramírez
In their recent publication Assan et al1 have shown that both IgG and IgA anti–Saccharomyces cerevisiae antibodies (ASCAs) are associated with hidradenitis suppurativa (HS).1 As the authors state, ASCA positivity has long been associated with Crohn disease and has recently been identified as a biomarker for spondyloarthritis (SpA). However, both Crohn disease and SpA comprise distinct phenotypes. The phenotype in Crohn disease can change from an inflammatory phenotype, to a fibrostenotic or penetrating phenotype with respectively severe stricturing or fistulation.
We read with interest the correspondence by van Straalen1 about our article reporting an association between anti –Saccharomyces cerevisiae antibodies (ASCAs) and hidradenitis suppurativa (HS), mainly in its severe and inflammatory forms, in comparison with healthy controls and severe psoriasis vulgaris.2
This population-based study examines the prevalence of cancer in patients with hidradenitis suppurativa.
Authors: Khanna R, Whang KA, Huang AH, Khanna R, Williams KA, Byrd AS, Okoye GA, Kwatra SG PMID: 32436763 [PubMed - as supplied by publisher]
Authors: Rosi E, Pimpinelli N, Prignano F PMID: 32432955 [PubMed - as supplied by publisher]
Hidradenitis suppurativa (HS) is a chronic-relapsing inflammatory disease affecting the apocrine gland-bearing skin and presenting with pseudocystic and inflammatory nodules, abscesses and fistulas .
Capsule Summary: Information on incidence of depression among children, adolescents and adults with hidradenitis suppurativa is limited. Pediatric and adult patients with hidradenitis suppurativa are at an increased risk for depression. Periodic screening for depression is warranted in patients with hidradenitis suppurativa, particularly among those who have additional risk factors.
This cohort study assesses the association of hidradenitis suppurativa with comorbidities that precede the diagnosis or develop after the diagnosis in Danish patients.