Sex Hormone Replacement Therapy in Turner Syndrome Sex Hormone Replacement Therapy in Turner Syndrome

Patients with Turner syndrome often require hormone replacement therapy, but what do we know about the long-term effects of this treatment?Journal of Clinical Endocrinology &Metabolism
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

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Autoimmune thyroid disease (ATD) is the most frequent cause of acquired thyroid dysfunction, most commonly presenting either as Hashimoto's thyroiditis or Graves' Disease. Hashimoto's thyroiditis is characterized by the presence of thyroid-specific autoantibodies, more commonly anti-thyroperoxidase antibodies in the serum and the typical inhomogeneous echostructure of the thyroid on a thyroid ultrasound examination. Hashimoto's thyroiditis can for a long time be accompanied by normal thyroid function and hypothyroidism can only progressively be established. Graves' disease is much less frequent in childhood and adolescence...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
AbstractTurner syndrome (TS) is associated with coronary artery disease (CAD), an important cause of premature death in TS. However, the determinants of CAD in women with TS remain unknown. In a cross-sectional study design, 168 women without clinical evidence of CAD (115 with TS and 53 without TS) were assessed for the presence and volume of subclinical CAD using coronary CT angiography. Karyotype, the presence of congenital heart defects and conventional cardiovascular risk factors were also registered. Comparative analyses were performed (1) between women with and without TS and (2) in the TS group, between women with a...
Source: Heart and Vessels - Category: Cardiology Source Type: research
AbstractCeliac disease (CD) is an immune-mediated enteropathy triggered by dietary ingestion of gluten in genetically susceptible patients. CD is often diagnosed by a “case-finding” approach of symptomatic patients. In recent times, the diagnostic paradigm has shifted to investigate patients who may be asymptomatic, but are at high risk of developing CD due to shared genetic susceptibilities. These high-risk groups include first-degree relatives of CD patient s and patients with Type 1 diabetes mellitus, autoimmune thyroid disease, Down’s syndrome, and Turner syndrome. Moreover, CD is often diagnosed as t...
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
Evaluation of the usefulness of antymüllerian hormone and inhibin B as markers of ovarian activity in patients with Turner syndrome - preliminary results. Pediatr Endocrinol Diabetes Metab. 2020 May 28;: Authors: Ruszała A, Wójcik M, Starzyk J Abstract INTRODUCTION: Spontaneous puberty occurs in 30% of patients with Turner Syndrome. Its absence is an indication for hormone replacement therapy (HRT). No reliable markers of spontaneous puberty have been defined to date. AIM OF THE STUDY: To evaluate the usefulness of antymüllerian hormone (AMH) and inhibin B assessment in predicti...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - Category: Endocrinology Authors: Tags: Pediatr Endocrinol Diabetes Metab Source Type: research
Turner syndrome can commonly result in ovarian insufficiency in females, which can impact reproductive function. What strategies may help preserve fertility in these patients?Clinical Endocrinology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
Women undergoing hormone therapy for Turner syndrome found to have reduced risk of diabetes, osteoporotic fractures and stroke, according to findings published inThe Journal of Clinical Endocrinology& Metabolism. Healio
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Abstract Celiac disease is a complex autoimmune enteropathy of the small intestine that commonly occurs in genetically predisposed individuals due to intake of gluten and related proteins. Gluten consumption, duration of breast-feeding, various infections, especially frequent intestine infections, vaccinations and use of antibiotics can be linked to celiac disease. It is predicted that it affects 1% of the global population and its incidence rate is increasing. Celiac disease is closely related to Turner's syndrome, type I diabetes mellitus, Down's syndrome, and other autoimmune conditions and most people with the...
Source: Current Pharmaceutical Biotechnology - Category: Biotechnology Authors: Tags: Curr Pharm Biotechnol Source Type: research
The genetic condition Turner syndrome can cause delayed puberty and is treated with estrogen replacement therapy. How does age at induction of puberty and type of ERT used impact health in adulthood?Journal of Clinical Endocrinology &Metabolism
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
Conclusions: Our study showed a higher incidence of autoimmune diseases in TS, which is in line with the literature; however, the impact of iXq, or spontaneous / inducted puberty was not confirmed.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
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