Dental Management of a Patient With Catecholaminergic Polymorphic Ventricular Tachycardia: A Case Report
Ventricular tachycardia (VT), which could lead to sudden cardiac death, occurs frequently in patients with myocardial infarction. Computational modeling has emerged as a powerful platform for the non-invasive investigation of lethal heart rhythm disorders in post-infarction patients and for guiding patient VT ablation. However, it remains unclear how VT dynamics and predicted ablation targets are influenced by inter-patient variability in action potential duration (APD) and conduction velocity (CV). The goal of this study was to systematically assess the effect of changes in the electrophysiological parameters on the induc...
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β-catenin/T-cell factor 4 (TCF4) signaling is enhanced in ischemic heart disease in which ventricular tachycardia/fibrillation (VT/VF) occurs frequently. How this signaling links to arrhythmogenesis remains unclear.
ConclusionsECMO support may be used for ablation procedures in patients with ES.This article is protected by copyright. All rights reserved.
PMID: 31109848 [PubMed - as supplied by publisher]
PMID: 31099757 [PubMed - as supplied by publisher]
In this study, we used a clinical dataset from a patient with a history of infarct-related VT to build an image-based 3D ventricular model aimed at computational simulation of cardiac EP, including detailed patient-specific cardiac anatomy and infarct scar geometry. We modeled the BZ in eight different ways by combining the presence or absence of electrical remodeling with four different levels of image-based patchy fibrosis (0%, 10%, 20% and 30%). A 3D torso model was also constructed to compute the ECG. Patient-specific sinus activation patterns were simulated and validated against the patient’s ECG. Subsequently, ...
Stereotaxis, a company that has developed robotic magnetic navigation technology to deliver catheters to the heart during ablation procedures, is introducing its latest generation system. The new Stereotaxis Genesis RMN platform features smaller magn...
THE BURDEN OF cardiac arrest out of hospital is substantial, with an estimated 424,000 cardiac arrests occurring each year in the United States and 275,000 in Europe.1,2 As few as 1 in 12 victims of cardiac arrest out of hospital survive to return home.3,4 Cardiac arrest secondary to a ventricular fibrillation (VF)/pulseless ventricular tachycardia (pVT) commonly employs the use of antiarrhythmic medications and interventions such as electrical defibrillation and chest compressions. If these medications have any effect on overall outcomes, neurological sequela in recovered victims, or discharge time, is still very nebulous.
In conclusion, susceptibility to lethal cardiac arrhythmia in SDS may be associated with specific changes in intracellular Ca2+ cycling components such as RYR2 due to mutation and dysregulation. Finding the probable association of SDS with gene defects can be applied to select for chickens with lower susceptibility to SDS and decrease the poultry industry losses due to SDS mortality. PMID: 31081346 [PubMed - as supplied by publisher]