Extramedullary Guide Alignment Is not Affected by Obesity in Primary Total Knee Arthroplasty

J Knee Surg DOI: 10.1055/s-0040-1701438Coronal alignment of the tibial implant correlates with survivorship of total knee arthroplasty (TKA), especially in obese patients. The purpose of this study was to determine if obesity affects coronal plane alignment of the tibial component when utilizing standard extramedullary tibial guide instrumentation during primary TKA. A retrospective review from June 2017 to February 2018 identified 142 patients (162 primary TKAs). There were 88 patients (100 knees) with body mass index (BMI) 
Source: Journal of Knee Surgery - Category: Orthopaedics Authors: Tags: Original Article Source Type: research

Related Links:

SummaryBackgroundPharmacological treatment options for adolescents with obesity are very limited. Glucagon ‐like‐peptide‐1 (GLP‐1) receptor agonist could be a treatment option for adolescent obesity.ObjectiveTo investigate the effect of exenatide extended release on body mass index (BMI) ‐SDS as primary outcome, and glucose metabolism, cardiometabolic risk factors, liver steatosis, and other BMI metrics as secondary outcomes, and its safety and tolerability in adolescents with obesity.MethodsSix ‐month, randomized, double‐blinded, parallel, placebo‐controlled clinical trial in patients (n = 44, 10‐18&thin...
Source: Pediatric Obesity - Category: Eating Disorders & Weight Management Authors: Tags: ORIGINAL RESEARCH Source Type: research
ConclusionsOur study provides fundamental insights on the molecular mechanisms underlying POMC neuron malprogramming in obesogenic contexts.Graphical abstract
Source: Molecular Metabolism - Category: Endocrinology Source Type: research
Authors: Bartelt A, Widenmaier SB Abstract The proper production, degradation, folding and activity of proteins, proteostasis, is essential for any cellular function. From single cell organisms to humans, selective pressures have led to the evolution of adaptive programs that ensure proteins are properly produced and disposed of when necessary. Environmental factors such as temperature, nutrient availability, pathogens as well as predators have greatly influenced the development of mechanisms such the unfolded protein response, endoplasmic reticulum-associated protein degradation and autophagy, working together in ...
Source: Biological Chemistry - Category: Chemistry Tags: Biol Chem Source Type: research
Consumers confronted with warnings on products that contain excess salt, sugar and calories
Source: FT.com - Drugs and Healthcare - Category: Pharmaceuticals Source Type: news
Discussion of the Evolutionary Genetics of Aging Thymic Involution Contributes to Immunosenescence and Inflammaging The Potential for Exosome Therapies to Treat Sarcopenia Correlations of Mitochondrial DNA Copy Number and Epigenetic Age Measures Evidence for PASK Deficiency to Reduce the Impact of Aging in Mice The Aging Retina, a Mirror of the Aging Brain Evidence for Loss of Capillary Density to be Important in Heart Disease Aspects of Immune System Aging Proceed More Rapidly in Men Deacetylation of the NLRP3 Inflammasome as a Way to Control Chronic Inflammation Transplantation of Senescent Cells is an ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Publication date: Available online 14 February 2020Source: Anaesthesia Critical Care &Pain MedicineAuthor(s): Audrey De Jong, Amélie Rollé, François-Régis Souche, Olfa Yengui, Daniel Verzilli, Gérald Chanques, David Nocca, Emmanuel Futier, Samir JaberAbstractThe obese patient is at risk of perioperative complications including difficult airway access (intubation, difficult or impossible ventilation), and postextubation acute respiratory failure due to the formation of atelectases or to airway obstruction. The association of obstructive sleep apnoea syndrome (OSA) with obesity is very ...
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
Publication date: Available online 14 February 2020Source: Anaesthesia Critical Care &Pain MedicineAuthor(s): Maha MA Mostafa, Ahmed M Hasanin, Fatema Alhamade, Bassant Abdelhamid, Ahmed G Safina, Sahar M Kasem, Osama Hosny, Mohamed Mahmoud, Eman Fouad, Ashraf Rady, Sarah M Amin
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
CONCLUSION: No higher prevalence of Mets among individuals with SO when compared to those with obesity only, nor a significant association between SO and higher risk of Mets was found. PMID: 32056530 [PubMed - as supplied by publisher]
Source: Current Cardiology Reviews - Category: Cardiology Tags: Curr Cardiol Rev Source Type: research
(Natural News) Cocoa (Theobroma cacao) is the main ingredient of chocolate, one of the most popular foods on the planet. The seeds of cocoa, also known as cocoa beans, are the only parts used for the production of chocolate. It is estimated that about nine tons of fresh byproducts — which end up as waste — are generated for each...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
AbstractBackground and aimsсomparative animal study of effectiveness of intermittent administration of lyophilized single-, three- and alive multistrain probiotic in short courses on insulin resistance (IR) in rats with experimental obesity.Methods70 rats were divided into 7 groups (n = 10 in each). Rats of group I were left intact. Newborn rats in groups II-VII were administered monosodium glutamate (MSG) (4 mg/g) by injection. Rats in group II (MSG-obesity group) were left untreated. The rats in groups III-V received lyophilized mono-probioticsB.animalis VKL,B.animalis VKB,L.casei IMVB-7280 respective...
Source: Journal of Diabetes and Metabolic Disorders - Category: Endocrinology Source Type: research
More News: Eating Disorders & Weight Management | Obesity | Orthopaedics | Study