FDG-PET/CT Assessment of Pulmonary Sarcoidosis: A Guide for Internists.

CONCLUSION: This review would illustrate the usefulness and limits of 18-F-FDG-PET/CT in the assessment of pulmonary sarcoidosis. PMID: 31964323 [PubMed - in process]
Source: Current Medical Imaging Reviews - Category: Radiology Tags: Curr Med Imaging Rev Source Type: research

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Authors: Elwazir MY, Bois JP, Abouezzeddine OF, Chareonthaitawee P Abstract Infiltrative heart disease is an encompassing term referring to different pathological entities that involve infiltration of the myocardium by either abnormal substances or inflammatory cells. These infiltrates can impair cellular function, induce necrosis and fibrosis, or otherwise disrupt myocardial architecture resulting in a wide spectrum of structural and functional impairment. Depending on the specific disorder and stage of disease, patients may present with minimal cardiac abnormalities, or may have findings of advanced restrictive a...
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Tags: Q J Nucl Med Mol Imaging Source Type: research
CONCLUSION: In this review, we would summarize in brief the clinical indications of PDG-PET in sarcoidosis and report the imaging features of the main organs involved in this disease. PMID: 31964321 [PubMed - in process]
Source: Current Medical Imaging Reviews - Category: Radiology Tags: Curr Med Imaging Rev Source Type: research
We present a case of a 73-year-old male who initially presented with night sweats, intermittent fever, worsening dry cough and shortness of breath. CT scans revealed atelectasis and calcified mediastinal lymphadenopathy, raising a suspicion for sarcoidosis. Multiple lung biopsies were performed. Microscopically, atypical lymphocytes were identified within capillaries, small arteries and veins. These lymphocytes were large with prominent nucleoli. Immunohistochemical staining demonstrated tumor cells positive for CD20, CD79a, Pax-5, CD10 and Mum-1, while negative for CD3, cytokeratin, S100, and CD34. LDH serum level was inc...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
ConclusionCommon variable immunodeficiency is a heterogeneous condition with a highly variable clinical phenotype and a strong association with autoimmune disorders. The presence of noncaseating granuloma and pulmonary lesions, along with extrapulmonary features required a step by step approach to differentiate between CVID and sarcoidosis. This enables early introduction of immunoglobulin replacement therapy and decreases the morbidity and mortality of CVID.
Source: International Journal of Rheumatic Diseases - Category: Rheumatology Authors: Tags: APLAR GRAND ROUND CASE Source Type: research
Publication date: Available online 13 December 2019Source: Academic RadiologyAuthor(s): Sarah M. Ryan, Brian Vestal, Lisa A. Maier, Nichole E. Carlson, John MuschelliRationale and ObjectivesA standard lung template could improve population-level analyses for computed tomography (CT) scans of the lung. We develop a fully automated preprocessing pipeline for image analysis of the lungs using updated methodologies and R software that results in the creation of a standard lung template. We apply this pipeline to CT scans from a sarcoidosis population, exploring the influence of registration on radiomic analyses.Materials and M...
Source: Academic Radiology - Category: Radiology Source Type: research
ConclusionsFMISO showed no physiological myocardial uptake and did not require special preparation. FMISO PET has the potential to detect hypoxic lesions in patients with sarcoidosis.
Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research
Conclusion: PET/CT added no significant additional benefit over Chest CT in patients with suspected OS or IOTB. PMID: 31743044 [PubMed - as supplied by publisher]
Source: Ocular Immunology and Inflammation - Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research
Conclusion: Awareness and identification of CVID associated respiratory abnormalities may guide therapy and improve prognosis.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Sarcoidosis and other granulomatous ILD/DPLD Source Type: research
Conclusion: Sarcoidosis patients with CPA or NTM exhibited GC pattern and had poor prognosis.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Sarcoidosis and other granulomatous ILD/DPLD Source Type: research
Introduction: Sarcoidosis is a granulomatous disease, and about 1-15% of patients with sarcoidosis show sinonasal involvements. Since, sinonasal involvements are similar to non-sarcoid rhinosinusitis and infectious rhinosinusitis and allergies, accurate diagnosis of Sinonasal Sarcoidosis (SNS) patients is mandatory to minimize unnecessary antibiotics and surgical treatments in sarcoidosis patients. This was the first study in Iran, to evaluate the SNS cases and their clinical presentations.Methods: In this cross-sectional study, eighty-eight biopsy proven sarcoidosis patients, with head and neck complaints, were included. ...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Sarcoidosis and other granulomatous ILD/DPLD Source Type: research
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