1198: Cytogenomic analysis of molar pregnancies as a frequent cause of sporadic and recurrent pregnancy loss

Partial and complete hydatidiform moles (PHM, CHM) are a common cause of pregnancy loss. To assess the frequency and nature of genomic imbalances, specifically polyploidy resulting in PHM and whole-genome uniparental disomy (WG-UPD) resulting in CHM, a comprehensive analysis of a large  cohort of miscarriage samples was analyzed by single nucleotide polymorphism (SNP)-based chromosomal microarray (CMA).

Source: American Journal of Obstetrics and Gynecology - December 31, 2019 Category: OBGYN Authors: Trilochan Sahoo, Natasa Dzidic, Jenna Guiltinan, Jeannine Oldzej, Rima Slim, Swaroop Aradhya, Karine Hovanes Tags: Poster Session V Source Type: research