U.S. Nursing Homes Reducing Use of Antipsychotic Drugs

Title: U.S. Nursing Homes Reducing Use of Antipsychotic DrugsCategory: Health NewsCreated: 8/27/2013 4:36:00 PMLast Editorial Review: 8/28/2013 12:00:00 AM
Source: MedicineNet Alzheimer - Category: Geriatrics Source Type: news

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Roche is testing its "brain shuttle" in humans, with the Swiss drugmaker hoping to rejuvenate the theory that removing amyloid plaques from the brains of patients with Alzheimer's disease will prove effective despite repeated failures.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Researchers at Lawrence Berkeley National Laboratory have developed synthetic peptide-coated magnetic beads that can be used to detect the presence of misfolded proteins in blood samples. Misfolded proteins are a factor in a number of diseases, inclu...
Source: Medgadget - Category: Medical Devices Authors: Tags: Diagnostics Nanomedicine Neurology Public Health Source Type: blogs
In 1990, Dr. Jack Kevorkian was just beginning his work in the death with dignity movement. Janet Adkins, who made a choice to die after being diagnosed with early Alzheimer’s disease, was his first assisted suicide patient. This week, Susan Clevenger publishes Dying to Die – The Janet Adkins Story. (Amazon) Clevenger interviewed and recorded stories from Janet’s family and closest friends, transcribed TV videos and read countless magazine and news stories. Her source material included Janet’s personal journals and letters from family and friends that the family had saved over the years.
Source: blog.bioethics.net - Category: Medical Ethics Authors: Tags: Health Care syndicated Source Type: blogs
This parallel-design, double-blind randomized clinical trial assesses the safety, tolerability, and pharmacodynamics of the microtubule stabilizer TPI-287 in patients with Alzheimer disease or the 4-repeat tauopathies progressive supranuclear palsy and corticobasal syndrome.
Source: JAMA Neurology - Category: Neurology Source Type: research
Authors: Kim YG, Park DG, Moon SY, Jeon JY, Kim HJ, Kim DJ, Lee KW, Han SJ Abstract BACKGROUND: Type 2 diabetes mellitus (T2DM) is associated with an increased risk for dementia. The effects of hypoglycemia on dementia are controversial. Thus, we evaluated whether hypoglycemia increases the risk for dementia in senior patients with T2DM. METHODS: We used the Korean National Health Insurance Service Senior cohort, which includes>10% of the entire senior population of South Korea. In total, 5,966 patients who had ever experienced at least one episode of hypoglycemia were matched with those who had not, using p...
Source: Diabetes and Metabolism Journal - Category: Endocrinology Tags: Diabetes Metab J Source Type: research
Nature Reviews Neurology, Published online: 11 November 2019; doi:10.1038/s41582-019-0289-7A high-salt diet leads to the development of hallmark Alzheimer disease (AD) pathology and cognitive impairment in mice, according to new research published in Nature. The study reveals previously unknown molecular mechanisms that could have therapeutic implications.
Source: Nature Reviews Neurology - Category: Neurology Authors: Source Type: research
Publication date: Available online 9 November 2019Source: Biochimica et Biophysica Acta (BBA) - General SubjectsAuthor(s): Abhishek Ankur Balmik, Rashmi Das, Abha Dangi, Nalini Vijay Gorantla, Udaya Kiran Marelli, Subashchandrabose ChinnathambiAbstractTau is the major neuronal protein involved in the stabilization of microtubule assembly. In Alzheimer's disease, Tau self assembles to form intracellular protein aggregates which are toxic to cells. Various methods have been tried and tested to restrain the aggregation of Tau. Most of the agents tested for this purpose have limitations in their effectiveness and availability ...
Source: Biochimica et Biophysica Acta (BBA) General Subjects - Category: Biochemistry Source Type: research
Nicotinamide phosphoribosyltransferase‑related signaling pathway in early Alzheimer's disease mouse models. Mol Med Rep. 2019 Oct 30;: Authors: Xing S, Hu Y, Huang X, Shen D, Chen C Abstract Alzheimer's disease (AD) is a neurodegenerative disease of the central nervous system that is characterized by progressive cognitive dysfunction and which ultimately leads to dementia. Studies have shown that energy dysmetabolism contributes significantly to the pathogenesis of a variety of aging‑associated diseases and degenerative diseases of the nervous system, including AD. One focus of research thus has be...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
When we think of dementia, we think of memory loss, but that's vastly oversimplifying it. Most people have heard of Alzheimer's, but there are other types of dementia too, says DR ELLIE..
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
DiscussionCMDs, especially when comorbid, are associated with increased dementia risk; however, leisure activities and social integration mitigate this risk.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
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