Thrombodynamics of Microvascular Repairs: Effects of Antithrombotic Therapy on Platelets and Fibrin

Conclusions: These findings show that platelets have a rapid, transient response, whereas fibrin has a slower, more sustained accrual in both arterial and venous anastomoses. Furthermore, inhibition of either coagulation or platelet aggregation can influence presumably non-targeted components of thrombosis in vascular repairs of both arteries and veins. Clinical relevance: Preventing replantation failure using antithrombotic therapies requires a better understanding of the effect of each pharmacologic compound on the various aspects of thrombogenesis.
Source: The Journal of Hand Surgery - Category: Surgery Authors: Tags: Scientific Articles Source Type: research