Unusual case of coexisting large intramyometrial anterior uterine wall leiomyoma with term pregnancy

We present a case of giant anterior wall leiomyoma complicating term pregnancy which posed a great surgical challenge. We didn’t go for myomectomy in the same setting because the patient was primigravida and leiomyoma occupied complete anterior wall of the uterus, an attempt of myomectomy could result in profuse uncontrollable bleeding.
Source: Medical Journal Armed Forces India - Category: General Medicine Source Type: research

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Publication date: Available online 30 January 2020Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Meritxell Gracia, Francisco CarmonaAbstractUterine myomas (fibroids, leiomyomas) are the most common benign myometrial tumors in women of reproductive age. They are present in 5-70% of women (depending on different series), with at least one fibroid identified in 70% of women aged 40 to 60 years. Symptoms are present in 20-50% of women with uterine fibroids and include Abnormal Uterine Bleeding (AUB), pelvic pain, Bulk-pressure symptoms and fertility problems depending on the size and ...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Uterine fibroids (UFs) are benign monoclonal neoplasms, representing the most common solid tumor of the female genital tract in reproductive-aged women. Despite the incidence being generally high worldwide (70% –80% in women by the age of 50 years), UFs affect ≤80% of women in some particular populations (African-American women). Furthermore, UFs are relative common in pregnancy and might negatively influence its outcomes (1). Uterine fibroids are generally asymptomatic; however, when symptoms occur, they might impair normal functioning and affect quality of life, most widely causing abnormal uterine bleeding...
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research
The North American Menopause Society (NAMS) held the 2018 Utian Translational Science Symposium on October 2, 2018, in San Diego, California, to discuss new therapeutic approaches to uterine leiomyomas when surgery is not the optimal choice. Uterine leiomyomas arise from a single clonal cell and are the most common gynecologic disorder affecting reproductive and perimenopausal women worldwide. The prevalence of this disorder is approximately 40% to 70% in white women and 60% to 80% in black women. Recent research suggests that both estrogen and progesterone modulate the growth of leiomyomas, with progesterone being a majo...
Source: Menopause - Category: OBGYN Tags: NAMS Translational Science Symposium Report Source Type: research
Abstract Abnormal uterine bleeding is a common symptom in women. The acronym PALM-COEIN facilitates classification, with PALM referring to structural etiologies (polyp, adenomyosis, leiomyoma, malignancy and hyperplasia), and COEIN referring to nonstructural etiologies (coagulopathy, ovulatory dysfunction, endometrial, iatrogenic, not otherwise classified). Evaluation involves a detailed history and pelvic examination, as well as laboratory testing that includes a pregnancy test and complete blood count. Endometrial sampling should be performed in patients 45 years and older, and in younger patients with a signifi...
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
ConclusionUterine sarcoma is a malignant tumour of the uterus that typically presents with vaginal bleeding, and rarely as prolapsed uterine inversion. Uterine inversion rarely occurs outside the puerperal setting; however, when it does occur, the possibility of an underlying malignancy should not be neglected.
Source: Case Reports in Womens Health - Category: OBGYN Source Type: research
A 28-year-old female, nulligravida, having regular menstruation previously, presented with 2 months of amenorrhea, right lower abdominal pain and vaginal bleeding for 1 day. On clinical examination, the patient was hemodynamically stable. Abdominal examination revealed right iliac fossa tenderness. Speculum examination revealed minimal vaginal bleeding. On vaginal examination, a normal sized uterus with an adnexal mass in right fornix was observed. Cervical motion tenderness was present. Urine pregnancy test was positive.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: Images in Gynecological Surgery Source Type: research
AbstractBACKGROUNDUterine leiomyoma (also known as fibroid or myoma) is the most common benign tumor of the uterus found in women of reproductive age. It is not usually fatal but can produce serious clinical symptoms, including excessive uterine bleeding, pelvic pain or pressure, infertility and pregnancy complications. Due to lack of effective medical treatments surgery has been a definitive choice for the management of this tumor.OBJECTIVE AND RATIONALEExtracellular matrix (ECM) accumulation and remodeling are thought to be crucial for fibrotic diseases such as uterine leiomyoma. Indeed, ECM plays important role in formi...
Source: Human Reproduction Update - Category: OBGYN Source Type: research
Authors: Gerome JM, Church TL Abstract Leiomyoma can be found concomitant with pregnancy and can cause complications during labor, delivery, and postpartum management. In the present case, a 26-year-old nulliparous patient at 39.4 weeks gestational age with a 12×9-cm retroplacental leiomyoma underwent a spontaneous vaginal delivery. Nine weeks after delivery, the patient presented with acute pain and vaginal bleeding. Immediate manual removal of the bulk of the leiomyoma tissue via vaginal approach was performed. Four weeks later, the patient returned for removal of the remaining tissue via hysteroscopic exci...
Source: Journal of the American Osteopathic Association - Category: Complementary Medicine Tags: J Am Osteopath Assoc Source Type: research
Conclusion TBA can replace vaginal hysterectomy in some perimenopausal women with uterine leiomyomas. Clinical Trials Registry India: CTRI/2016/07/007119.
Source: International Journal of Gynecology and Obstetrics - Category: OBGYN Source Type: research
CONCLUSIONS Despite the high contraceptive effectiveness of many hormonal and intrauterine reversible contraceptive methods, many HCPs, users and potential users are concerned mainly about side effects and safety of both hormonal and non-hormonal contraceptive methods, and there is scarce information about the many benefits that these methods offer beyond contraception.
Source: Human Reproduction Update - Category: OBGYN Authors: Tags: Reviews Source Type: research
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