Klippel-Feil syndrome: a review of the literature

Klippel-Feil syndrome is a congenital defect in the formation or segmentation of the cervical spine. A wide spectrum of associated anomalies may be present. This heterogeneity has complicated clarification of the genetic causes and management of patient’s with congenital vertebral fusion. In this review, we focussed on clinical heterogeneity; radiographic abnormalities and genetic etiology in Klippel-Feil syndrome. We insist on comprehensive evaluation and delineation of diagnostic and prognostic classes.
Source: Clinical Dysmorphology - Category: Genetics & Stem Cells Tags: Review Article Source Type: research

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Publication date: February 2020Source: Journal of Comparative Pathology, Volume 175Author(s): H. Ariyarathna, N. Thomson, D. Aberdein, J.S. MundaySummaryTumour histological classification and grade are frequently used to predict the prognosis of canine mammary gland tumours. While these techniques provide some information about tumour behaviour, it is currently difficult to predict which tumours will metastasize. Mast cell density has been shown to predict metastasis in human breast cancer. The present study investigated whether the average mast cell density in 10 high-power (×400) microscopical fields (10 HPFs), eva...
Source: Journal of Comparative Pathology - Category: Pathology Source Type: research
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Source: Acta Orthopaedica - Category: Orthopaedics Authors: Source Type: research
Conclusion: Our series details the unusual circumstances when an eye is removed for intraocular lymphoma. Different patterns of ocular tissue involvement were observed when we compared primary and secondary lymphomas.
Source: RETINA - Category: Opthalmology Tags: Clinicopathologic Correlation Source Type: research
We report a case of a 15-year-old adolescent who presented with a single pulmonary nodule on a chest radiograph, in the context of a respiratory infection, and whose etiological investigation revealed an inflammatory myofibroblastic tumor of the lung. Atypical resection was performed by video-assisted thoracoscopic surgery, with full recovery. We highlight the rarity of this entity, the need for a high suspicion index and the diagnostic investigation undertaken to reach a definitive diagnosis and a successful outcome. PMID: 31958395 [PubMed - as supplied by publisher]
Source: Acta Medica Portuguesa - Category: General Medicine Tags: Acta Med Port Source Type: research
Students studying to become paramedics, radiographers and physiotherapists will be among those receiving the new financial support from September 2020
Source: Disabled World - Category: Disability Tags: United Kingdom Source Type: news
This study was conducted to evaluate the clinical effectiveness treatment effects of a simple buccal technique for maxillary molar distalization using direct buccal skeletal anchorage.Materials and methodsAfter sample size calculation, fourteen female patients with bilateral Class II molar relationship (age 11–14 years) were selected from the clinic of the Department of Orthodontics, Faculty of Dentistry, Mansoura University, Egypt. After the application of the eligibility criteria, only eleven patients remained to final evaluation. The criteria included: erupted second maxillary molars, mild to moderate maxillary cr...
Source: International Orthodontics - Category: Dentistry Source Type: research
CONCLUSION: Ultrasound could be as sensitive and specific as contrast-enhanced MRI for the diagnosis of subclinical synovitis and tenosynovitis.
Source: Clinics - Category: General Medicine Source Type: research
AbstractPurposeLower limb malalignment is a strong predictor of progression in knee osteoarthritis. The purpose of this study is to identify the individual alignment variables that predict progression in early to moderate osteoarthritis of the knee.Method A longitudinal cohort study using data from the Osteoarthritis Initiative. In total, 955 individuals (1329 knees) with early to moderate osteoarthritis (Kellgren-Lawrence grade 1, 2 or 3) were identified. All subjects had full-limb radiographs analysed using the Osteotomy module within Medicad® Classic (Hectec GMBH) to give a series of individual alignment var...
Source: Knee Surgery, Sports Traumatology, Arthroscopy - Category: Orthopaedics Source Type: research
This article investigates the clinical, functional, and radiographic outcomes in anterior cruciate ligament (ACL) reconstruction patients over 7 years to determine the effects of initial graft tension on outcomes when using patellar tendon (bone–tendon–bone [BTB]) and hamstring tendon (HS) autografts. Ninety patients, reconstructed with BTB or HS, were randomized using two initial graft tension protocols: (1) normal anteroposterior (AP) laxity (“low-tension”; n = 46) and (2) AP laxity overconstrained by 2 mm (“high-tension”; n = 44). Seventy-two patient...
Source: Journal of Knee Surgery - Category: Orthopaedics Authors: Tags: Original Article Source Type: research
ConclusionsC-shaped root canals were more prevalent in mandibular second molars and in females. Additionally, clinicians should bear in mind the greater possibility of C-shaped configuration in mandibular molars with fused roots.Clinical relevanceMandibular molars with C-shaped canals present a clinical challenge. A higher C-shaped proportion was noted in radiographic fused root types, which had 17.2 higher odds of presenting such anatomy when compared to radiographic non-fused roots. Root radiographic features may help in diagnosis of complex C-shaped morphologies.
Source: Clinical Oral Investigations - Category: Dentistry Source Type: research
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