The iScore Predicts Efficacy and Risk of Bleeding in the National Institute of Neurological Disorders and Stroke Tissue Plasminogen Activator Stroke Trial

The iScore is a validated tool to estimate outcomes after an acute ischemic stroke. A previous study showed the iScore can predict clinical response and risk of intracerebral hemorrhage (ICH) after administration of tissue plasminogen activator (tPA). We applied the iScore (www.sorcan.ca/iscore) to participants in the National Institute of Neurological Disorders and Stroke tPA stroke trials to evaluate its ability to estimate clinical response and risk of ICH after thrombolysis. Based on results from our previous study, patients were stratified a priori into iScore

Source: Journal of Stroke and Cerebrovascular Diseases - October 26, 2012 Category: Neurology Authors: Gustavo Saposnik, Andrew Demchuk, Jack V. Tu, S. Claiborne Johnston, Stroke Outcomes Research Canada (SORCan) Working Group Tags: Original Articles Source Type: research