A 22-Year-Old Man With Extreme Leg Pain: USMLE Question A 22-Year-Old Man With Extreme Leg Pain: USMLE Question
A 22-year-old man presents with leg pain. He was treated for a right tibial fracture the previous day. He now rates his pain as a 10 on a 10-point scale. What's the next step?Osmosis
In this study, we reported a new case of primary DSRCT of the tibia in a 33-year-old man who had intermittent pain in the left tibia. Radiographs showed transparent lesions in the left upper tibial. MRI revealed a lobular, lytic and ill-identified lesion with adjacent soft tissues swelling of the upper left tibia. CT confirmed notable destruction and wormlike osteolysis of the bone cortex. PET/CT showed a mass of high uptakes, indicating the malignance. He accepted surgical resection with followed multi-agent chemotherapy, containing vincristine, doxorubicin, ifosfamide and etoposide. Clinically and radiologically, the pat...
CONCLUSION: Hyperthermic Mitomycin using the HIVEC® device is a rather safe and well tolerated treatment. Efficiency remains partial as 27.3% of patients experienced recurrence during the first year. These data should be confirmed by prospective multicentric studies. PMID: 31787540 [PubMed - as supplied by publisher]
Authors: Stoustrup P, Herlin T, Spiegel L, Rahimi H, Koos B, Pedersen TK, Twilt M, Temporomandibular joint Juvenile Arthritis Work group (TMJaw) Abstract OBJECTIVE: To develop a consensus-based, standardized, short clinical (
CONCLUSION: Lack of relief of pain or restoration of function or quality of life or the occurrence of surgical complications after TJR were defined as TJR failure by participants. Functional TJR failure seems as or more important than surgical failure. This patient perspective of TJR failure further confirmed their inclusion in core domain set for TJR clinical trials in people undergoing knee or hip replacements. PMID: 31787606 [PubMed - as supplied by publisher]
Authors: Kuettel D, Primdahl J, Weber U, Terslev L, Østergaard M, Petersen R, Pedersen AK, Möller S, Hørslev-Petersen K Abstract OBJECTIVE: To examine prospectively self-reported flare characteristics and their longitudinal association with disease activity and patient-reported outcomes (PROs) in patients with rheumatoid arthritis (RA). METHODS: Consecutive RA patients with DAS28CRP
Authors: Di Carlo M, Muto P, Benfaremo D, Luchetti MM, Atzeni F, Salaffi F Abstract OBJECTIVE: To evaluate the prevalence and factors associated with the neuropathic pain features in a cohort of patients with psoriatic arthritis (PsA). METHODS: A cross-sectional evaluation was conducted in consecutive patients suffering from PsA with prevalent peripheral joint involvement, referring to three rheumatological centers. For each patient a comprehensive assessment of disease activity, physical function, and disease impact was carried out. The presence of comorbid fibromyalgia syndrome (FMS) was evaluated. Acute phas...
This study describes the clinical and radiographic outcomes of patients treated with expandable interbody spacers for MIS LLIF.MethodsA retrospective, single surgeon, clinical and radiographic study was performed on 37 consecutive patients who underwent MIS LLIF at 1–2 contiguous level(s) using expandable spacers. Radiographic and clinical functional outcomes were collected and compared at preoperative and postoperative time points up to 12 months. Parametric and nonparametric tests were used when appropriate with p value
Publication date: Available online 3 December 2019Source: Journal of PhysiotherapyAuthor(s): Shankar Ganesh
Conclusion: Functional diarrhea was associated with hemodynamic indices of sympathetic activation, supporting a possible role of the autonomic nervous system in diarrhea. PMID: 31791149 [PubMed - as supplied by publisher]