Multi-component solvent-free cascade reaction of 2-cyanoacetamides with ketones and acetone: highly regioselective synthesis of functionalized pyridin-2-ones bearing quaternary centers

Green Chem., 2019, Accepted Manuscript DOI: 10.1039/C9GC03692J, PaperLing-Bin Kong, Rong Huang, Hao-Dan He, Yun-Xiang Fan, Jun Lin, Sheng-Jiao Yan A novel protocol has been constructed for the synthesis of four types of pyridin-2-ones (2 −5) via a solvent-free cascade reaction of 2-cyanoacetamides 1, various ketones, and acetone via multicomponent reactions... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Green Chem. latest articles - November 25, 2019 Category: Chemistry Authors: Ling-Bin Kong Source Type: research