Diffuse Hyperpigmentation Can Distinguish Chikungunya From Other Arbovirus Infections Diffuse Hyperpigmentation Can Distinguish Chikungunya From Other Arbovirus Infections

With outbreaks of chikungunya fever (CF) having been reported in previously untouched regions from southern Europe to the Americas, clinicians need to be aware of even such relatively rare signs of the infection as acquired diffuse hyperpigmentation, researchers say.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

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Authors: Maniero VC, Rangel PSC, Coelho LMC, Silva CSB, Aguiar RS, Lamas CC, Cardozo SV Abstract A progressive increase in the circulation of arboviruses in tropical countries has been observed, accounting for 700,000 yearly deaths in the world. The main objective of this article was to identify the presence of Zika (ZIKV), dengue (DENV), and Chikungunya (CHIKV) viruses in immature stages of Aedes aegypti and Ae. albopictus. Household collections of immature phases of the vectors were carried out in the years 2015 and 2016. A total of 2902 dwellings were visited and the rate of infestation with larvae and pupae of ...
Source: Brazilian Journal of Medical and Biological Research - Category: Research Tags: Braz J Med Biol Res Source Type: research
Conclusions: Aedes albopictus is responsible for the current outbreaks. The spread of Aedes albopictus and Aedes japonicus increases the risk of the autochthonous transmission of these viruses. Although native species could contribute to their transmission, more studies are still needed to assess that risk.
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
[Radio Dabanga] Khartoum -Sudan has been facing various disease outbreaks in the past months, including cholera, dengue fever, Rift Valley fever (RVF), chikungunya, and malaria. The government and humanitarian partners actively responded to the outbreaks, the UN Office for the Coordination of Humanitarian Affairs (OCHA) reports. Most complaints reaching Radio Dabanga come from the western and eastern parts of the country.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Abstract Chikungunya is an arthropod-borne viral disease characterized by abrupt onset of fever frequently accompanied by joint pain, which has been identified in over 60 countries in Africa, Americas, Asia, and Europe. Regardless of the availability of molecular knowledge of this virus, no definite vaccine or other remedial agents have been developed yet. In the present study, a combination of B-cell and T-cell epitope predictions, followed by molecular docking simulation approach has been carried out to design a potential epitope-based peptide vaccine, which can trigger a critical immune response against the vir...
Source: Current Pharmaceutical Biotechnology - Category: Biotechnology Authors: Tags: Curr Pharm Biotechnol Source Type: research
by V íctor Hugo Peña-García, Rebecca C. Christofferson Chikungunya virus (CHIKV) emerged in Colombia in 2014 into a population presumed fully susceptible. This resulted in a quick and intense spread across Colombia, resulting in an epidemic that affected an estimated 450,000 people. The reported Colombian cases accounted for over 49% of all the cases reported to the PAHO. Eco-environmental factors are known to be associated with the spread of arboviruses such as CHIKV, and likely contribute to the differences in transmission profiles that were observed across several municipalities. To determine the a...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
While efforts to control malaria with available tools have stagnated, and arbovirus outbreaks persist around the globe, the advent of clustered regularly interspaced short palindromic repeat (CRISPR)-based gene editing has provided exciting new opportunities for genetics-based strategies to control these diseases. In one such strategy, called “population replacement”, mosquitoes, and other disease vectors are engineered with effector genes that render them unable to transmit pathogens. These effector genes can be linked to “gene drive” systems that can bias inheritance in their favor, providing nove...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
[Radio Dabanga] Khartoum -Sudan has been facing numerous disease outbreaks including dengue fever, Rift Valley fever (RVF), and chikungunya in the past months.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
[Radio Dabanga] Khartoum -Sudan has been facing numerous disease outbreaks including dengue fever, Rift Valley fever (RVF), and chikungunya in the past months.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Chikungunya virus (CHIKV) infection is one of the most challenging re-emergent diseases caused by a virus, and with no specific antiviral treatment it has now become a major public health concern. In this investigation, 25 blood samples were collected from patients with characteristic CHIKV symptoms and submitted to a virus isolation protocol, which detected 3 CHIKV isolates. These samples were evaluated by sequencing for the characterization of the strains and any homology to viruses circulating in Brazil during a recent outbreak. These viruses were used for the development of antiviral assays. Subsequently, the inhibitor...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Chikungunya Virus-Encoded nsP2, E2, and E1 Strongly Antagonizes the Interferon β Signaling Pathway. J Microbiol Biotechnol. 2019 Oct 22;: Authors: Bae S, Lee JY, Myoung J Abstract Chikungunya virus (CHIKV) is a single-stranded positive-sense RNA virus, belonging to the genus alphavirus of the Togaviridae family. It causes multiple symptoms, including headache, fever, severe joint and muscle pain, and arthralgia. Since CHIKV was first isolated in Tanzania in 1952, there have been multiple outbreaks of CHIKV. However, its pathogenesis and mechanisms of viral immune evasion have been poorly understo...
Source: Journal of Microbiology and Biotechnology - Category: Biotechnology Authors: Tags: J Microbiol Biotechnol Source Type: research
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