First African American Face Transplant Performed First African American Face Transplant Performed

Robert Chelsea suffered burns in 2013. In 2015, the United Network of Organ Sharing began a new allocation system aimed at a more racially equitable selection process of who receives a transplant.WebMD Health News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Transplantation News Source Type: news

Related Links:

CIBMTR previously showed that centralized PRO collection from patients treated at multiple transplant centers (TC) was feasible; however, consenting by sites and the paper mode of collection were logistically challenging. CIBMTR built an electronic system (ePRO), and we report our initial experience.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: 87 Source Type: research
Despite increasing donor options for allogeneic transplantation, including matched/mismatched related donors, matched unrelated donors and cord blood units, a proportion of patients do not find a donor. This is especially relevant in patients from racial/ethnic minorities. Post-transplant cyclophosphamide (PTCY) has successfully overcome barriers related to HLA-mismatching in the related donor setting. We hypothesized that transplantation with a mismatched unrelated donor (MMUD) using PTCY would be feasible and associated with high engraftment and acceptable GVHD incidence.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: 432 Source Type: research
Decisions about research priorities are made based on what are thought to be the most pressing scientific questions, in the context of current knowledge and perceived advances. However, research moves slowly while real-world experience accumulates and new approaches are introduced. Adoption of new practices before they have been adequately compared to current treatments are threats to successful conduct of the studies and may expose patients to what is ultimately learned to be inferior treatment.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: 296 Source Type: research
Autologous hematopoietic cell transplantation (autoHCT) is considered standard-of-care for transplant-eligible patients with newly diagnosed multiple myeloma (MM). In 2016, 8776 autoHCTs were performed for MM in the United States (US), increasing from 5621 in 20101. With advances in supportive care resulting in outcomes comparable to those of younger patients, there is an increasing use of autoHCT in older patients [2,3]. Patients aged ≥70 years represented 12% of the over 14,000 autoHCTs performed in 20162.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Source Type: research
Abstract Existing epidermal transplantation procedures applied in burn surgery or wound treatment, such as mesh grafting or the Meek method, do not lead to a restoration of all the skin layers. Dermal skin layers are indispensable in ensuring the quality and function of the transplanted skin as a frictional surface and a carrier of skin appendages such as hair, sweat glands, and sebaceous glands, as well as nerve receptors for detecting pressure, vibration, and temperature. Because of the restricted skin surface area that can be provided by the donor, full-skin transplants cannot be transplanted over a large area....
Source: Annals of Anatomy - Category: Anatomy Authors: Tags: Ann Anat Source Type: research
Publication date: Available online 19 December 2019Source: Medicina Intensiva (English Edition)Author(s): M. Sánchez-Sánchez, J.R. Martínez, B. Civantos, Pablo MillánAbstractBurned patients may need prolonged admissions in the Intensive Care Service, both for initial care and for the pre and postoperative treatment of the multiple surgeries they require. The initial resuscitation of critically burned patients requires adequate monitoring to calculate the fluid therapy necessary to replenish the losses and ensure tissue perfusion, but without excesses that increase interstitial edema. In addition...
Source: Medicina Intensiva - Category: Intensive Care Source Type: research
AML patients receiving killer immunoglobulin-like receptor (KIR) mismatched  haploidentical HSCT have improved survival. COG AAML05P1 is a prospective phase 2 trial of unrelated donor (URD) HSCT in which KIR typing of donors was available to the treating physician at donor selection, aiming to determine feasibility (defined as the ability to obtain donor samples from unr elated donors and perform and return KIR data before transplant) of prospective selection of KIR mismatched donors and effect on outcomes.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Source Type: research
Killer immunoglobulin-like receptor (KIR) genes participate in the regulation of natural killer (NK) cell function, and mismatch between transplant donor and recipient improves clinical outcomes in some transplantation settings [1-6]. Lower than expected rates of relapse, graft failure, and graft-versus-host disease (GVHD) occur in KIR-incompatible, T cell-depleted, HLA-mismatched related donor hematopoietic stem cell transplantation (HSCT) for acute myelogenous leukemia (AML) [5]. Similarly, Hsu et al [7] reported superior overall survival (OS) and disease-free survival (DFS) for recipients of KIR-incompatible HCST compar...
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Source Type: research
In this study, we use platelet-rich plasma gel as an adipose-derived stem cell scaffold to assist the growth of rat skin grafts. ADSCs were successfully isolated and seeded into the PRP gel. Using a Lewis rat model, we found the PRP gel + ADSCs significantly improved the properties of the transplanted skin grafts, increased the skin thickness and improved the collagen arrangement. PRP gel + ADSCs promoted skin neovascularization by elevating the expression of the vascularization factors VEGF, BFGF and PDGFB. Taken together, our study indicated that ADSCs combined with PRP have a potentiation eff...
Source: Burns - Category: Dermatology Source Type: research
CONCLUSIONS: The webinars met the educational needs of learners and improved knowledge gaps. This study provided novel insights into the learning needs of clinicians who care for patients with AML and a roadmap for future educational interventions. PMID: 31805525 [PubMed - in process]
Source: Journal of the National Comprehensive Cancer Network : JNCCN - Category: Cancer & Oncology Tags: J Natl Compr Canc Netw Source Type: research
More News: Burns | Health | Transplant Surgery | Transplants