Application of apparent diffusion coefficient values derived from diffusion-weighted imaging for assessing different sized metastatic lymph nodes in cervical cancers.

Application of apparent diffusion coefficient values derived from diffusion-weighted imaging for assessing different sized metastatic lymph nodes in cervical cancers. Acta Radiol. 2019 Oct 15;:284185119879686 Authors: Aining Z, Song J, Ma Z, Chen T PMID: 31615267 [PubMed - as supplied by publisher]
Source: Acta Radiologica - Category: Radiology Authors: Tags: Acta Radiol Source Type: research

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Pharmaco-epigenomics: On the Road of Translation Medicine. Adv Exp Med Biol. 2019;1168:31-42 Authors: López-Camarillo C, Gallardo-Rincón D, Álvarez-Sánchez ME, Marchat LA Abstract Epigenomics refers to the study of genome-wide changes in epigenetic mechanisms including DNA methylation, histone modifications and non-coding RNAs expression. The alterations in normal DNA methylation and histone acetylation/deacetylation patterns lead to deregulated transcription and chromatin organization resulting in altered gene expression profiles that facilitates tumor development and ...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
[Nation] Kenya is on course in the immunisation of 800,000 girls against cervical cancer, Health Cabinet Secretary Sicily Kariuki has said, and allayed fears about the safety of the vaccine.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Source: OncoTargets and Therapy - Category: Cancer & Oncology Tags: OncoTargets and Therapy Source Type: research
Conclusion: EP provides monolayered cervical smears with vivid morphological details, leading to reduced screening time and relatively higher pick-up of infections and low-grade cervical lesions as compared to conventional smears. The availability of such low-cost devices may enable wider application of cytology-based cervical cancer screening in low-resource countries.
Source: CytoJournal - Category: Pathology Authors: Source Type: research
Conclusion: We developed a nomogram to predict lymph node metastasis in patients with early-stage endometrial cancer in China. This prediction model may help clinicians in decision-making for patients with early-stage endometrial cancer, especially for the patient with incomplete surgery, reducing overtreatment, and medical costs.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
A case-control study was used to explore the association between the methylation status in the promoter regions of the cGAS, MAVS, and TRAF3 genes and the diseases of cervical precancerous lesions (CPL) and cervical cancer (CC) in a Southern Chinese population, and to further explore their interaction effects with high-risk human papillomavirus (hrHPV) infection and environmental factors in these diseases. The study protocol was approved by the ethics committee of The First Affiliated Hospital of Jinan University, and this study was performed in 97 healthy controls, 75 patients with CPL and 33 patients with CC, while each ...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Publication date: Available online 12 November 2019Source: Meta GeneAuthor(s): Rinki Singh, Anup SomAbstractOvarian, cervical and endometrial cancers are the most common gynecological cancers affecting women worldwide. Overall, the molecular mechanism of the disease is not well understood. These cancers have similar embryological origin which has led to the hypothesis that they might share common genes and pathways for disease development. In order to find out pathways and key candidate genes shared by these three lethal gynecological cancers, we performed comparative gene expression analysis for the three types of cancers...
Source: Meta Gene - Category: Genetics & Stem Cells Source Type: research
Publication date: Available online 12 November 2019Source: Preventive MedicineAuthor(s): Michelle I. Silver, Sarah KobrinAbstractThe human papillomavirus (HPV) vaccine is a powerful tool in cancer prevention. In combination with cervical cancer screening programs, this vaccine has the potential to nearly eliminate death from cervical cancer. However, this remarkable public health success can only be realized if vaccines reach those most at risk—unscreened women. Vaccinating only those already well-screened would have little impact on cervical cancer mortality, exacerbate disparities, and be a striking public health f...
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
ConclusionThe surgical treatment of postirradiation kyphotic spinal deformity is challenging, with common postoperative complications such as infection, instrumentation failure, and pseudarthrosis. However, with modern surgical techniques and spinal instrumentation, excellent deformity correction can be achieved and maintained. We recommend performing a two-stage procedure for cervicothoracic deformity, with anterior release followed by posterior fusion and instrumentation. In thoracolumbar deformities, correction can be achieved through single-stage posterior fusion. Rigid spinopelvic fixation with sacral-alar-iliac screw...
Source: Spine Deformity - Category: Orthopaedics Source Type: research
Publication date: Available online 12 November 2019Source: Preventive MedicineAuthor(s): Susannah Gibbs, S. Marie Harvey, Linh Bui, Lisa Oakley, Jeff Luck, Jangho YoonAbstractWe evaluated the effect of the Affordable Care Act (ACA) Medicaid expansion on receipt of preventive reproductive services for women in Oregon. First, we compared service receipt among continuing Medicaid enrollees pre- and post-ACA. We then compared receipt among new post-ACA Medicaid enrollees to receipt by continuing enrollees after ACA implementation. Using Medicaid enrollment and claims data, we identified well-woman visits, contraceptive counsel...
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
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