Investigation of Bosentan's Effects on Pulmonary Contusion Created by Blunt Thoracic Trauma in Rats

Conclusion PC causes progressive lung tissue damage. Bosentan reduced leukocyte infiltration and alveolar edema and congestion caused by PC. It also decreased MDA levels and increased SOD levels. Bosentan prevents tissue damage by inhibiting acute inflammatory response and reduces oxidative stress secondary to inflammation. It has therapeutic effects on apoptosis. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text

Source: European Journal of Pediatric Surgery - October 9, 2019 Category: Surgery Authors: Gercel, Gonca Aksu, Burhan Ozkanli, Seyma Uzun, Hafize Aksu, Feyza Ozatman, Erdem Durakba şa, Çiğdem Ulukaya Tags: Original Article Source Type: research