Discovery of Novel Small Molecules that Block Myofibroblast Formation: Implications for Capsular Contracture Treatment

Conclusions: Several novel small molecules with anti-TGF-β activity can effectively prevent human capsular fibroblast to myofibroblast differentiation in vitro, even in the presence of radiation. These results highlight novel therapeutic options that may be utilized in the future to prevent radiation-induced capsular contracture.
Source: Plastic and Reconstructive Surgery – Global Open - Category: Cosmetic Surgery Tags: Experimental Source Type: research