Sleep disturbances may increase risk Alzheimer's disease risk in Hispanic people

In the short-term, sleep disorders cause an inconvenience. But over time, researchers say, these disorders can increase risk for Alzheimer's disease, with greatest risk coming for Hispanic people.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news

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Traumatic brain injury (TBI) and Alzheimer's disease (AD) are diseases during which the fine-tuned autoregulation of the brain is lost. Despite the stark contrast in their causal mechanisms, both TBI and AD are conditions which elicit a neuroinflammatory r...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news
(RMIT University) New research shows damage in the brain starts in the same place and spreads in the same way in sleep apnea, as in Alzheimer's disease. The study is the first to find Alzheimer's-like amyloid plaques in the brains of people with clinically-verified obstructive sleep apnea, a condition that affects more than 936 million people worldwide.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
This study included a carefully selected cohort of females with mild-moderate AD confirmed by biological evaluation (n = 29). The individuals were submitted to one-night PSG to diagnose OSA (apnea-hypopnea index ≥ 15/h) and the blood was collected in the following morning. The plasma miRNA profile was evaluated using RT-qPCR. The patients had a mean (SD) age of 75.8 (5.99) years old with a body mass index o f 28.6 (3.83) kg m−2. We observed a subset of 15 miRNAs differentially expressed between OSA and non-OSA patients, of which 10 were significantly correlated with the severity of OSA. B...
Source: Molecular Neurobiology - Category: Neurology Source Type: research
DEMENTIA symptoms include memory loss, difficulty concentrating, and having slower thoughts. But you could be raising your risk of Alzheimer's disease signs by sleeping in a certain way. Should you change your sleep position to protect against dementia?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Treatment of obstructive sleep apnea with positive airway pressure was associated with a lower odds of incident Alzheimer's disease and other dementia in a large retrospective cohort study.Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news
This article gives a summary of the main results of MEL therapy in some neurological diseases and insomnia approved by this consensus group. Exogenous MEL, which crosses the blood-brain barrier, has been used as a treatment in its two available forms: an immediate release form that principally shows a chronobiotic action and a long release form that mimics the physiological MEL secretion rhythm and is used to replace reduced physiological secretion. MEL secretion decreases frequently with age, mostly in elderly insomniacs and dementia patients. Results of level A studies show that MEL therapy, used as an add-on treatment, ...
Source: Revue Neurologique - Category: Neurology Tags: Rev Neurol (Paris) Source Type: research
Sleep inhibition induced by amyloid-β oligomers is mediated by the cellular prion protein. J Sleep Res. 2020 Sep 09;:e13187 Authors: Del Gallo F, Bianchi S, Bertani I, Messa M, Colombo L, Balducci C, Salmona M, Imeri L, Chiesa R Abstract Sleep is severely impaired in patients with Alzheimer's disease. Amyloid-β deposition in the brain of Alzheimer's disease patients is a key event in its pathogenesis and is associated with disrupted sleep, even before the appearance of cognitive decline. Because soluble amyloid-β oligomers are the key mediators of synaptic and cognitive dysfunction in A...
Source: Journal of Sleep Research - Category: Sleep Medicine Authors: Tags: J Sleep Res Source Type: research
BackgroundIn March 2020, the World Health Organization declared a global pandemic due to the novel coronavirus SARS-CoV-2 and several governments planned a national quarantine in order to control the virus spread. Acute psychological effects of quarantine in frail elderly subjects with special needs, such as patients with dementia, have been poorly investigated. The aim of this study was to assess modifications of neuropsychiatric symptoms during quarantine in patients with dementia and their caregivers.MethodsThis is a sub-study of a multicenter nation-wide survey. A structured telephone interview was delivered to family ...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
CONCLUSION: The NPI is a useful tool to detect NPS in those with MCI-LB. The MCI-LB group had a higher prevalence of core features (visual hallucinations and RBD) and a higher LBNSSC than the MCI-AD group. These features could help to differentiate MCI-LB and MCI-AD. PMID: 32896168 [PubMed - as supplied by publisher]
Source: Aging and Mental Health - Category: Geriatrics Authors: Tags: Aging Ment Health Source Type: research
(University of California - Berkeley) UC Berkeley neuroscientists have found a way to estimate, with some degree of accuracy, a time frame for when Alzheimer's is most likely to strike in a person's lifetime, based on their baseline sleep patterns. Their findings suggest one defense against this virulent form of dementia -- for which no treatment currently exists -- is deep, restorative sleep, and plenty of it.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
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