Pfizer settles patent lawsuit with Teva, Sun Pharma for $2.15 billion

(Reuters) - Pfizer Inc said it reached a $2.15 billion settlement with Teva Pharmaceuticals Industries Ltd and Sun Pharmaceutical Industries Ltd related to patent infringement on its acid-reflux drug Protonix.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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ConclusionPatients with ineffective esophageal motility derive significant benefits in perioperative and QOL outcomes after LARS. Nevertheless, as anticipated, their baseline dysmotility may reduce the degree of improvement in dysphagia rates post-surgery compared to patients with normal motility. Furthermore, the presence of preoperative IEM should not be a contraindication for complete fundoplication. Key to optimal outcomes after LARS is careful patient selection based on objective perioperative data, including manometry evaluation, with the purpose of tailoring surgery  to provide effective reflux control and impr...
Source: Surgical Endoscopy - Category: Surgery Source Type: research
FRIDAY, Sept. 18, 2020 -- Coffee, tea, and soda are associated with an increased risk for gastroesophageal reflux (GER) symptoms among middle-aged women, according to a study published in the September issue of Clinical Gastroenterology and...
Source: - Pharma News - Category: Pharmaceuticals Source Type: news
Conclusions: The prevalence of erosive tooth wear in enamel and dentin was relatively high in Lithuania; the erosive tooth wear in enamel and dentin combined was 52% among 35- to 44-year-olds, 68% among 45- to 54-year-olds, 67% among 55- to 64-year-olds, and 63% among 65- to 74-year-olds. Lower fluoride level in drinking water was associated with erosive tooth wear in enamel. Male gender, residency in periurban/rural areas, older age, and presence of acid reflux were associated with higher odds, while higher D3MFS scores were associated with lower odds for erosive tooth wear in dentin. These results can be used to plan den...
Source: Caries Research - Category: Dentistry Source Type: research
Conclusion. Double-flap PG is technically feasible through a single incision with the use of articulating laparoscopic devices and intra-abdominal organ retractors to assist in intracorporeal anastomosis. PMID: 32938322 [PubMed - as supplied by publisher]
Source: Surgical Innovation - Category: Surgery Authors: Tags: Surg Innov Source Type: research
This study aimed to examine the clinical utility of prolonged wireless reflux monitoring to predict ability to discontinue PPI.
Source: Gastroenterology - Category: Gastroenterology Authors: Source Type: research
This article discusses both elective and emergency benign disorders of the OGJ, including their investigation and management. Elective conditions include gastro-oesophageal reflux disease (GORD), giant para-oesophageal hiatal herniae (GPHH), achalasia and other motility disorders. These conditions are now usually all managed laparoscopically when operative intervention is required.
Source: Surgery (Medicine Publishing) - Category: Surgery Authors: Tags: Oesophagus and stomach Source Type: research
The oesophagus is subject to a number of disorders affecting motility (swallowing) including gastro-oesophageal reflux disease, malignancy and disorders of neuromuscular function, such as achalasia. Most neoplasms of the oesophagus and stomach are epithelial in nature. Benign epithelial neoplasms usually take the form of polypoid lesions, such as oesophageal squamous papillomas, gastric adenomas, hyperplastic and fundic gland polyps. Malignant epithelial neoplasms of the oesophagus are divided into squamous cell carcinoma and adenocarcinoma, whereas malignant gastric neoplasms are predominantly adenocarcinomas.
Source: Surgery (Medicine Publishing) - Category: Surgery Authors: Tags: Basic science Source Type: research
is a lethal condition where 5-year survival remains at about 15%. There are two main subtypes of oesophageal cancer, squamous cell carcinoma (OSCC) and adenocarcinoma (OAC). OSCC usually affects the middle third of the oesophagus and is associated with smoking, alcohol and low socio-economic status. OAC affects the lower third of the oesophagus and is associated with gastro-oesophageal reflux disease. The UK has the highest incidence of OAC in the world and it is rising. Treatment may be palliative or curative.
Source: Surgery (Medicine Publishing) - Category: Surgery Authors: Tags: Oesophagus and stomach Source Type: research
CONCLUSION: Tension-free crural repair with non-absorbable mesh does not reduce the incidence of recurrent hiatal hernia compared with use of sutures alone in patients undergoing laparoscopic fundoplication. NCT03730233 ( PMID: 32936951 [PubMed - as supplied by publisher]
Source: The British Journal of Surgery - Category: Surgery Authors: Tags: Br J Surg Source Type: research
Conclusion Regular dental counseling adopting the multidisciplinary team approach for patients with EA is necessary to ensure better general and oral health. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: European Journal of Pediatric Surgery - Category: Surgery Authors: Tags: Original Article Source Type: research
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