Behçet disease: An uncommon condition with common manifestations

This article uses a case study to explore the diagnosis of BD.
Source: The Nurse Practitioner - Category: Nursing Tags: Feature: CHRONIC INFLAMMATORY CONDITIONS: CE Connection Source Type: research

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ConclusionsMutations of MEFV can contribute to increase inflammatory expression in other diseases, as Kawasaki disease.
Source: Italian Journal of Pediatrics - Category: Pediatrics Source Type: research
Publication date: Available online 16 October 2019Source: Respiratory Medicine Case ReportsAuthor(s): Midori Yamada, Kei Nakashima, Hiroyuki Ito, Masahiro AoshimaAbstractCorticosteroid therapy may not be enough to control pneumonitis in some cases of severe drug-induced lung injury (DLI); however, an advanced treatment strategy for such cases is lacking. Here, we report the case of an 88-year-old man who presented with severe DLI, caused by Sai-rei-to. The patient visited our hospital complaining of progressive dyspnea. High-resolution computed tomography of the chest demonstrated bilateral patchy ground-glass opacities an...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Takayasu ’s arteritis (TA) is a systemic large vessel vasculitis that affects the aorta and its branches. Most patients with TA respond to medical therapy with a minority of patients requiring surgical intervention. In our report we describe the case of a 59-year-old Caucasian female with TA who underwent revascularization due to cerebrovascular symptoms refractory to medical therapy. She initially presented with amaurosis fugax and developed episodes of syncope and slurred speech during corticosteroid tapering.
Source: Annals of Vascular Surgery - Category: Surgery Authors: Tags: Case Report Source Type: research
HIV infection may affect cardiovascular system through different physio pathological patterns including viral vasculitis, thrombophilia induction, opportunistic infection, major HIV vasculo-tropic coinfections and secondary effects of antiretroviral therapy. Vessel pathology may manifest as obstructive disease, dissection or aneurysm conditions that may involve major , medium or small vessels, in different arterial branches.Rarely reported in HIV negative patients , aneurysms involving carotid artery have been described for the first time in seropositive patients in 1989.
Source: Annals of Vascular Surgery - Category: Surgery Authors: Tags: General Review Source Type: research
AbstractA massive but asymptomatic left subclavian artery pseudoaneurysm was diagnosed in a 30-year-old female patient with transposition of the great arteries, ventricular septal defect, and pulmonary atresia. After undergoing bilateral modified Blalock –Taussig shunts at the age of 4 months and 3 years, respectively, she underwent the Rastelli operation and division of both shunts at the age of 6 years of age. The pseudoaneurysm was not discovered at the follow-up investigation at age 14. During the time period from age 18 to 30 years, she w as lost to follow-up, she was confirmed to be free fro...
Source: General Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
AbstractRecent advances have allowed better understanding of vasculitis pathogenesis and led to more targeted therapies. Two pivotal randomized controlled trials, RITUXVAS and rituximab in ANCA-associated vasculitis (RAVE), provide high-quality evidence demonstrating rituximab (RTX) is efficacious in inducing remission in adult ANCA-associated vasculitis (AAV) patients compared with cyclophosphamide (CYC). RAVE also demonstrated superiority of RTX to oral CYC for induction of remission in relapsing disease. Disappointingly, the RTX regimen was not associated with reduction in early serious adverse events. At least nine ran...
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
CONCLUSION: SIE are common in patients with TAK and occur early in the disease. With aggressive treatment, patients with SIE had a favourable prognosis. PMID: 31615911 [PubMed - as supplied by publisher]
Source: J Rheumatol - Category: Rheumatology Authors: Tags: J Rheumatol Source Type: research
In this study, we investigated whether hypereosinophilia (peripheral eosinophil  ≥ 1500/mm3) at diagnosis could estimate the increased current activity and predict the poor prognosis during follow-up in patients with eosinophilic granulomatosis with polyangiitis (EGPA). We retrospectively reviewed the medical records of 42 patients with EGPA and finally included 30 systemic immunosuppressive drug-na ïve patients. We obtained clinical and laboratory data including clinical manifestations, Birmingham vasculitis activity score (BVAS), five-factor score (FFS) (2009), and routine laboratory results. Hypere...
Source: Rheumatology International - Category: Rheumatology Source Type: research
AbstractThe pathogenesis of the immunoglobulin A vasculitis (IgAV) is still unknown. The available data shows that interleukin (IL)-17, IL-18, IL-23, regulated on activation, normal T cell expressed and secreted (CCL 5, RANTES), and interferon (IFN)- γ-inducible protein 10 (IP10) participate in the pathogenesis of IgAV by influencing the recruitment of leukocytes to the site of inflammation. The aim of this study was to analyze the serum concentration of IL-17A, IL-18, IL-23, RANTES, and IP10 in patients with acute IgAV compared to healthy chil dren. Moreover, we wanted to assess the suitability of the levels of test...
Source: Rheumatology International - Category: Rheumatology Source Type: research
We report two cases of AAV with different renal manifestations associated with cocaine consumption. Furthermore, we performed a review of the literature to identify, characterize and describe h istologically documented cases of renal involvement in AAV, related to cocaine abuse. Cocaine/levamisole-induced vasculitis may, therefore, mimic idiopathic AAV. Although the detection of ANCA and anti-PR3 (proteinase 3, PR3) as well as anti-MPO antibodies (myeloperoxidase, MPO) are the serological hallmark of idiopathic AAV, certain clinical- and antibody constellations should lead to consideration of illicit drugs as inductors of ...
Source: Rheumatology International - Category: Rheumatology Source Type: research
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