Which Fat Processing Can Achieve Optimal Transplantation in Patients With Insufficient Fat Resource?

Background Autologous fat transfer has been widely used in breast augment surgery. The breast fat graft is different form facial, it needs megavolume grafts. However, most Asian women are thin, who often encounter the fat resource insufficiency during breast augmentation. In fact, some processing methods do contribute to great loss of potential fat that could have been grafted. How to choose a best processing method to achieve optimal transfer in patients with insufficient fat resources is fairly important. Methods Lipoaspirate was obtained from 10 healthy female patients who underwent liposuction from abdomen. According to the processing methods, 10-mL initial fat grafts divided into 4 groups: decantation (group A), centrifugation (group B), cotton pad (group C), and cell-assisted lipotransfer (CAL) (group D). Lipoaspirate from each group was compared in the vitro and vivo experiments. The content and function of stromal vascular fraction (SVF) were compared as well as lipoaspirate survival after grafting in nude mice. Results The SVFs were counted in decantation group 4.32 ± 0.75 × 106/mL, centrifuge group 3.48 ± 0.78 × 106/mL, cotton pad group 1.64 ± 0.84 × 106/mL, CAL group 4.08 ± 0.73 × 106/mL. The decantation group was higher than the cotton pad group (P
Source: Annals of Plastic Surgery - Category: Cosmetic Surgery Tags: Research Source Type: research