Reuters asks judge to release secret Propecia documents

Reuters asked a U.S. judge on Thursday to unseal documents filed in court regarding potential risks associated with Propecia, Merck&Co's popular baldness drug.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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HAIR loss is a common phenomenon, especially as people get older, but that doesn't make it any less upsetting. There are a number of cosmetic options available to treat hair loss but if you are looking for a natural solution, a nutritional-based supplement has shown promising results.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Authors: Gul A, Gul M, Ozsoy S, Sarac T, Celik DS, Semercioz A, Serefoglu EC Abstract OBJECTIVES: Although the association between 5 alpha reductase inhibitors used for the treatment of both androgenetic alopecia and benign prostatichy perplasia and their side effects is well established, the impact of dutasteride on testicular structure is not clear. To evaluate the alterations in spermatogenesis and serum FSH, LH, testosterone and dihydrotestosterone concentrations along with the oxidative status in testes and blood of the rats treated with daily dutasteride. METHODS: A total of 18 male Sprague-Dawley rats ha...
Source: Archivos Espanoles de Urologia - Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research
Authors: Mahmoudi H, Rostami A, Tavakolpour S, Nili A, Teimourpour A, Salehi Farid A, Abedini R, Amini M, Daneshpazhooh M Abstract Background: Frontal fibrosing alopecia (FFA) is a scarring alopecia with no promising treatment.Objective: To evaluate the additive efficacy of oral isotretinoin to topical treatments.Methods: Between November 2017 and August 2018, FFA patients were randomly assigned to receive either isotretinoin (20mg/d) plus topical treatments (clobetasol 0.05% and tacrolimus 0.1%) or monotherapy with topical treatments. Treatments' efficacy was evaluated through Frontal Fibrosing Alopecia Severity I...
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
Conclusion: The overall prevalence of AA among a population of Saudi patients is 2.3%. AA prevalence is higher in pediatrics than adults. Common comorbid conditions include hypothyroidism, diabetes mellitus, and atopic diseases. PMID: 32231700 [PubMed]
Source: Dermatology Research and Practice - Category: Dermatology Tags: Dermatol Res Pract Source Type: research
Authors: Asfour L, Yiu ZZN, Warren RB Abstract Introduction: Skin conditions are common and highly varied in their etiology; therefore, a diverse array of therapeutics are utilized. Drug safety studies in dermatology can be challenging as there are over 3000 diagnoses to consider. As a result, dermatologists rely on data from multiple sources including clinical trials and real-world evidence.Areas covered: In this review, we cover the main sources of safety data available, their strengths and weaknesses and how dermatologists should utilize such data. We use real-world examples of the different types of adverse eve...
Source: Expert Opinion on Drug Safety - Category: Drugs & Pharmacology Tags: Expert Opin Drug Saf Source Type: research
HAIR loss can strike anyone, and the causes range from genetics to stress. Thankfully there is one of the oldest treatments out there which could help with hair loss. What is it?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Here’s an excerpt from the Revised &Expanded Edition of Wheat Belly, page 184: I had a heck of a time persuading Gordon to drop the wheat. I met Gordon because he had coronary disease. Among the causes: abundant small LDL particles along with the usual accompaniments of low HDL, high triglycerides, and high blood sugar. I asked him to completely remove the wheat from his diet in order to reduce or eliminate the small LDL particles and thereby obtain better control over heart health. Problem: Gordon owned a bakery. Bread, rolls, and muffins were part of his everyday routine, three meals a day, seven days a week. I...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Open alopecia areata grain-free hair loss Inflammation wheat belly Source Type: blogs
CONCLUSION Most studies on PRP report favorable outcomes with the strongest level of evidence existing for androgenetic alopecia followed by postprocedure wound healing, scar revision, striae, rejuvenation, and dermal filling. There is a dearth of large randomized controlled trials, considerable heterogeneity in the variables studied, and lack of specificity in the preparatory protocols, which may influence clinical outcomes. Future investigations should use consistent nomenclature, find ideal solution parameters for each cutaneous indication, determine significant outcome metrics, and follow double-blinded, randomized, ...
Source: Dermatologic Surgery - Category: Dermatology Tags: Review Article Source Type: research
Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Genome binding/occupancy profiling by high throughput sequencing Mus musculus Source Type: research
Contributors : Hanseul Yang ; Rene Adam ; Elaine FuchsSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusTissue homeostasis and regeneration rely upon resident stem cells (SCs), whose behavior is regulated through niche-dependent crosstalk. The mechanisms underlying SC maintenance are still unfolding. Here, using hair follicles (HFs) as model and spatiotemporal gene ablation in mice, we uncover transcription factors (TFs) NFIB and NFIX as guardians of the process. Complete NFI ablation causes SC depletion and hair loss which resembles irreversible alopecia in humans, who in...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Genome binding/occupancy profiling by high throughput sequencing Mus musculus Source Type: research
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