Wild polio has been eradicated in Nigeria but infections will continue
Nigeria has officially wiped out wild polio, but there have already been 15 cases of infection this year, caused by the live virus used in some vaccines
Background: Whilst wild polio outbreaks are becoming a distant memory, vaccine-derived poliovirus (VDPV) outbreaks are increasing in incidence. For many countries currently experiencing VDPV outbreaks (Philippines, Ghana, Indonesia, etc.) it has been many years since polio has been observed and the optimal location of vaccination campaigns are uncertain.
[Cameroon Tribune] Surprisingly, the toughest resistance to the vaccination of children against the debilitating disease is from residents of Bafoussam, Douala and Yaounde.
(American Chemical Society) Vaccines have curtailed the spread of several infectious diseases, such as smallpox, polio and measles. However, vaccines against some diseases, including HIV-1, influenza and malaria, don't work very well, and one reason could be the timing of antigen and adjuvant presentation to the immune system. Now, researchers reporting inACS Central Science developed an injectable hydrogel that allows sustained release of vaccine components, increasing the potency, quality and duration of immune responses in mice.
AbstractGlobally coordinated cessation of all three serotypes of oral poliovirus vaccine (OPV) represents a critical part of a successful polio endgame, which the Global Polio Eradication Initiative (GPEI) plans to conduct in phases, with serotype 2 OPV cessation completed in mid 2016. Although in 2016 the GPEI expected to globally coordinate cessation of the remaining OPV serotypes (1 and 3) by 2021, continuing transmission of serotype 1 wild polioviruses to date makes those plans obsolete. With increasing time since the last reported polio case caused by serotype 3 wild poliovirus (in November 2012) leading to high confi...
[Ghanaian Times] Ho -- Recent social media reports alleging that the polio vaccine rather leaves children vulnerable to the virus are totally false, absolutely baseless and wholly-ridiculous, according to Dr Kwesi Djokoto, Deputy Director of Health (DDH) in charge of public health in the Volta Region.
[Seychelles News Agency] Public health authorities in Seychelles are urging residents to continue to take the vaccine against polio, which hasn't been seen in Seychelles since 1966.
[PR Newswire] Amman, Jordan -- "The recent vaccine-derived polio outbreaks confirmed in Yemen and Sudan are consequences of increasingly low levels of immunity among children. Each outbreak has paralysed children in areas that have been extremely difficult if not impossible to reach with routine or supplementary polio vaccination for extended periods of time.
[Cameroon Tribune] He was in the Littoral and Centre Regions for three days to raise awareness on the benefits of vaccination.
[Cameroon Tribune] Cameroonian star rapper, Stanley Enow, held a press conference in Yaounde on September 10, 2020 to close a three-day tour to raise awareness on polio vaccination.
Abstract Infection is the predominant cause of mortality in early life, and immunization is the most promising biomedical intervention to reduce this burden. However, very young infants fail to respond optimally to most vaccines currently in use, especially neonates. In 2005, Stanley Plotkin proposed that new delivery systems would spur a new revolution in pediatric vaccinology, just as attenuation, inactivation, cell culture of viruses, genetic engineering, and adjuvantation had done in preceding decades. Recent advances in the field of immunoengineering, which is evolving alongside vaccinology, have begun to inc...