Medical News Today: Inflammation in type 2 diabetes: Study overturns previous notions

New research challenges the prevalent belief that it is glucose that drives chronic inflammation in obesity and obesity-related type 2 diabetes.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Diabetes Type 2 Source Type: news

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AbstractPurpose of ReviewRecent advances in genomics provide opportunities for novel understanding of the biology of human traits with the goal of improving human health. Here, we review recent obesity and type 2 diabetes (T2D) –related genomic studies in African populations and discuss the implications of limited genomics studies on health disparity and precision medicine.Recent FindingsGenome-wide association studies in Africans have yielded genetic discovery that would otherwise not be possible; these include identification of novel loci associated with obesity (SEMA-4D,PRKCA,WARS2), metabolic syndrome (CA-10,CTNN...
Source: Current Diabetes Reports - Category: Endocrinology Source Type: research
Patients with obesity and type 2 diabetes who underwent bariatric surgery were less likely than those on medical treatment to have coronary, cerebrovascular or kidney events, in new observational data.Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - Category: Neurology Tags: Cardiology News Source Type: news
'Sensibly optimistic systematic review does not provide definitive evidence that true incidence is falling ’ Related items fromOnMedica Scotland reveals target of halving child obesity by 2030 Obesity as cause of cancer set to overtake smoking Should we recognise obesity as a disease? Type 2 diabetes in 10 times more young people than realised Even athletes can ’t outrun the effects of a bad diet
Source: OnMedica Latest News - Category: UK Health Source Type: news
ConclusionsWe conclude the review by emphasizing missing knowledge gaps that remain and future research opportunities needed to implement FKBP51 as a drug target for stress-related obesity or T2D.
Source: Molecular Metabolism - Category: Endocrinology Source Type: research
Diabetes has grown to become one of the most important public health concerns of our time. A review by the Harvard T.H. Chan School of Public Health has shown that the number of affected people has quadrupled in the last three decades. Type 2 diabetes (T2D), a type of diabetes traditionally occurring in adults and associated with obesity and a sedentary lifestyle, is now the ninth leading cause of death worldwide. It therefore comes as no surprise that this rapidly emerging epidemic is giving rise to a profusion of diabetes-related complications. What are the usual diabetes-related complications? As diabetes is a systemic ...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Diabetes Health Source Type: blogs
Youths with obesity and type 2 diabetes who had greater insulin sensitivity and higher levels of adiponectin displayed better response to insulin therapy, according to a study published inPediatric Diabetes.Healio
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
Authors: Rahman V Abstract Obesity is a national and global epidemic and is usually the result of a poor diet and lifestyle. Obesity is a strong risk factor for type 2 diabetes and cardiovascular disease, which are leading causes of morbidity and mortality. Ample scientific evidence supports that nutritional interventions involving plant-based diets can be effective in the prevention and treatment of obesity, diabetes, and cardiovascular disease. Many patients are interested in improving their eating habits and frequently look to physicians for dietary advice. However, most physicians are unable to provide meaningf...
Source: The Permanente journal - Category: General Medicine Tags: Perm J Source Type: research
Authors: Pasquali R, Oriolo C Abstract Androgen excess is often associated with obesity states, at any age of life, because of changes in the pattern of secretion or metabolism of androgens and in their actions at the level of target tissues, particularly the adipose tissue. Androgen excess plays an important role in favouring the expansion of visceral fat, which characterize so-called visceral obesity. Moreover, there is evidence that the combination of androgen excess and obesity may favour the development of metabolic disorders, such as the metabolic syndrome and type 2 diabetes. In obese adolescent girls, andro...
Source: Frontiers of Hormone Research - Category: Endocrinology Tags: Front Horm Res Source Type: research
Conclusions: MetS is associated with physical inactivity and unhealthy diet. To increase LTPA recommendations and raise awareness in the population about the health benefits of PA and high adherence to MD is highly recommended.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
ConclusionsChinese adults had the higher prevalence of prediabetes and T2DM and a higher probability of T2DM at the same BMI level compared with Swedish adults. These results indicate the importance of addressing the ongoing obesity epidemic as a matter of urgency in order to curb what has become an apparent diabetes epidemic in both countries.
Source: Diabetes Therapy - Category: Endocrinology Source Type: research
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